ISB News

NIH Awards $45M to Alzheimer’s Research

The National Institutes of Health announced $45 million in grants to support several research groups that are focused on Alzheimer's prevention. ISB's Price Lab will be working with the University of Florida to use systems biology to identify new therapeutic targets in the innate immune system. The systems approach, which ISB pioneered, allows scientists to integrate and analyze disparate data (genome, gene expression, pathology) in order to find the molecular…

$500K Proof of Concept Grants Awarded to ISB Scientists

Photo: ISB’s Jennifer Smith speaks to Jose Banda, superintendent of Seattle Public Schools, in this archived photo. Jennifer just received a $250,000 grant from the Life Sciences Discovery Fund. The Life Sciences Discovery Fund announced the recipients of $1.25 million in Proof of Concept grants. ISB’s Brady Bernard, of the Shmulevich Group, and Jennifer Smith, of the Aitchison Group, each will receive grants totaling almost $500,000. From the LSDF press…

Awards: ‘Seven over 70’ Best Innovators

Dr. Lee Hood, ISB’s president, was named one of Seven Over 70 best innovators in MIT Technology Review Magazine. The list recognizes leaders for their lifelong achievements in innovation. Here’s an excerpt from the story: ” ‘The physician and biologist Leroy Hood helped create the fields of genomics and proteomics by inventing the protein sequencer, the protein synthesizer, the DNA synthesizer, and, most important of all, the automated DNA sequencer. He later…

Collaboration: $16.6M TB Grant

ISB will collaborate with Seattle BioMed and ETH Zurich on a $16.6 million tuberculosis grant from the National Institutes of Health. Seattle BioMed issued this press release today: FOR IMMEDIATE RELEASE SEATTLE, AUG. 15 — Seattle BioMed has been awarded a grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, that will take a comprehensive systems approach to the problem of tuberculosis…

ISB in Antarctica: Researcher Receives Medal

Allison Lee, who traveled to Antarctica this spring aboard a research cruise on an icebreaker in the Ross Sea, just received an Antarctic Service Medal for her participation. The medal was created by Congress and presented by the National Science Foundation to those who serve on a U.S. expedition to Antarctica. Allison is a member of the Nitin Baliga Lab and has been working closely with senior research scientist Mónica Orellana,…

Ranish Lab Receives $156K Grant

Congratulations to ISB faculty member Jeff Ranish and his group on receiving a new grant for $156,000. The award is for collaborative work with Peter Myler at Seattle BioMed on “Base J and transcription termination in Leishmania.” Here’s the public health relevance statement from the proposal: Human infections with the various species of Leishmania parasite cause substantial morbidity and mortality in tropical and sub-tropical countries world-wide. These organisms appear to…

ISB Recieves $1.8M Grant for Ocean Acidification Research

Congratulations to Dr. Mónica Orellana and Dr. Nitin Baliga on their new grant for $1.8 million from the National Science Foundation. The project title is “Ocean Acidification: A Systems Biology Approach to Characterize Diatom Response to Ocean Acidification and Climate Change.” Abstract from the proposal: Diatoms account for approximately 40 percent of primary production in the world’s oceans and are the most productive marine phytoplankton group. They form the basis…

Dr. Lee Hood Honored for Inspiring Future Scientists

Dr. Lee Hood during the Northwest Association for Biomedical Research’s annual fundraising event on June 4, 2013. Dr. Hood received the Alvin J. Thompson Award for inspiring future scientists. Previous winners of this award from ISB include Dr. Nitin Baliga and Dr. Lee Rowen. Photo by Chris Witwer/ISB.

BBC Radio: Dr. Lee Hood on P4 Medicine

Dr. Lee Hood gave the keynote speech at the Future in Review conference on May 21. During the conference, Hood was presented with “CEO of the Year” award. In this BBC Business Daily segment, host Ed Butler talks to Hood about his P4 vision. Listen Now

ISB Post Doc Gets Patent for Protein that Blocks HIV

Martin Shelton Martin Shelton, a post doc in the Lee Hood lab, just received his first patent. He shared the following explanation with his 10-year-old nephew who’s a burgeoning scientist/inventor/engineer. “We made a small molecule called a peptide (which is a sciency word for a piece of a protein). This peptide blocks a function that is key to the spread of the Human Immunodeficiency Virus (HIV, the virus that causes…

ISB Takes 1st Place in YarcData Contest

Dr. Brady Bernard, Andrea Eakin, and Dr. Ilya Shmulevich, of The Institute for Systems Biology (ISB), were awarded first prize and will split $70,000 for their winning entry researching more than 25 different types of cancers and thousands of patients to gain insight into the biological networks that are disrupted or altered within a given cancer type and to identify potentially potent approved drugs that could be repurposed for the…

National Medal of Science Profile of Dr. Lee Hood

Dr. Lee Hood Receives National Medal of Science

Above: Dr. Lee Hood and members of his lab group raise a very Seattle toast with Starbucks coffee to celebrate. On Dec. 21, 2012, the White House announced that Dr. Lee Hood, ISB’s president and co-founder, is a recipient of the 2012 National Medal of Science. This is the highest honor the U.S. President can bestow upon scientists. “This is exciting because it’s for lifetime achievement,” Lee commented, “which lauds all…

National Academy of Inventors 2012 Charter Fellow: Dr. Lee Hood

This is the press release from the National Academy of Inventors: National Academy of Inventors announces 2012 NAI Charter Fellows 98 academic inventors and innovators elected to high honor TAMPA, Fla. (Dec. 18, 2012)—The National Academy of Inventors (NAI) has named 98 innovators to NAI Charter Fellow status, representing 54 prestigious research universities and non-profit research institutes. Together, the new Fellows hold more than 3,200 U.S. patents. Included in the…

Price Lab Pre-Doc Is Awarded a Harvard Junior Fellowship

ISB is proud to announce that Sriram Chandrasekaran, one of our predoctoral scientists in the Nathan Price group, has received one of 10 Harvard Junior Fellowships. This prestigious fellowship grants Sriram the opportunity to pursue an independent research project without the pressure of having to secure funding and with mentoring from faculty at Harvard and MIT. It’s a “sexy way of transitioning to a tenure-track faculty position.” The rigorous interview…

Members of Hood Lab Win First Place in the IMPROVER Diagnostic Signature Challenge

Kai Wang, Ji Hoon Cho and intern Alan Lin, all of Dr. Lee Hood’s group, participated in the IMPROVER Diagnostic Signature Challenge and won first place for the psoriasis sub-challenge. IMPROVER stands for Industrial Methodology for Process Verification in Research; it’s a method for verifying scientific data and concepts in systems biology research.

Juan Caballero Solves InnoCentive Challenge

Juan Caballero, a post doctoral fellow in Dr. Lee Hood’s group, answered an open call through InnoCentive for a solution to combat Citrus Greening Disease, which affects about 18 percent of citrus trees in Florida. He was awarded $10,000 for designing the right RNAi to control the viral disease.

Science Education Honors

In June, Dr. Nitin Baliga, ISB’s director for integrative biology, was presented with the 2012 Alvin J. Thompson Award for his significant contributions to bringing systems science education to high schools throughout Washington State and beyond. In August, Zhihao Tan and Michelle Hays, members of the Aimée Dudley group, took first place in the graduate student poster competition at the Genetics Society of America’s Yeast Genetics and Molecular Biology Meeting…