ISB News

John Gillotte

ISB Research On Long COVID Featured in the New York Times

In an article published by Pam Belluck for the New York Times titled, “New Research Hints at 4 Factors That May Increase Chances of Long Covid,” findings of an ISB-led study published in the journal Cell are covered in depth, including quotes from ISB president Dr. Jim Heath.

Predicting ‘Long COVID’ At Initial Point of COVID-19 Diagnosis

Researchers have identified several factors that can be measured at the initial point of COVID-19 diagnosis that anticipate if a patient is likely to develop long COVID. They also found that mild cases of COVID-19, not just severe cases, are associated with long COVID. Their findings were published by the journal Cell.

Spotlight on ISB Education graphic

2021-22 School Year ISB Education Highlights

From planning, creating and executing workshops for educators to forging new relationships to elevate students, the ISB Education team has been in high gear. Each month throughout the 2021-2022 academic year, we will highlight some of the top projects the team is working on.

Maternal COVID-19 Infection Increases Risks of Preterm Birth, Low Birth Weight and Stillbirth

An ISB-led study examined the electronic health records of more than 18,000 people with SARS-CoV-2 tests during pregnancy, and found that those who contracted COVID-19 while pregnant were more likely to have poor birth outcomes including preterm birth, small for gestational age, low birth weight, and stillbirth.

Anna Kuchina

Dr. Anna Kuchina Joins ISB as Assistant Professor

Dr. Anna Kuchina has joined ISB as assistant professor, and is our newest faculty member. Kuchina comes to ISB after completing her postdoctoral training in the Seelig Lab at the University of Washington. In this Q&A, we delve into Kuchina’s research career to date, her research areas of interest, and much more.

Miranda Johnson

Get to Know Miranda Johnson, ISB’s First-Ever AmeriCorps Member

This past fall, AmeriCorps member Miranda Johnson packed her bags and left her home state of Illinois to join ISB as a Systems Thinkers in STEM Coordinator. Johnson is the first AmeriCorps member at ISB, so we had quite a few questions about how she got here, her experience thus far, and her future plans.

Cultivated meat illustration

How Systems Biology Is Helping Advance the Cultivated Meat Industry

The quest to create cultivated meat has been a true multidisciplinary puzzle. It’s biology, engineering, physics, bioinformatics, mathematics, computer science, and more. Enter systems biology. ISB and other organizations are toiling to better understand how to create lab-grown meat in a safe, effective manner that can eventually scale up to compete with traditional meat.

Baliga, Peterson and Srinivas

ISB Creates Algorithms To Accelerate Discovery of Efficacious Treatments for Tuberculosis

Tuberculosis (TB) is the world’s second leading infectious disease killer after COVID-19. Drug resistance to TB is a public health crisis. ISB researchers have developed algorithms to predict the efficacy of drugs in treating Mycobacterium tuberculosis (MTB), the causative agent for TB. These research findings were published in the journal Cell Reports Methods.

Dr. Jack Gilbert on the State of the Microbiome Field

In the final ISB-Town Hall Seattle Science Series of 2021, ISB Assistant Professor Dr. Sean Gibbons sat down with UCSD Professor Dr. Jack Gilbert, and the two microbiome experts discussed past research, exciting science happening today, promising products and therapies on the horizon, and much more.

Reimagine: Your Immune System Event Generates $60,000 to Fuel Critical ISB Research

More than 300 people registered for Reimagine: Your Immune System, ISB’s annual virtual fundraiser, for an evening that included guest appearances Nobel laureate Dr. David Baltimore, immunology expert Dr. Mark Davis, ISB President Dr. Jim Heath, and a host of ISB researchers studying the human immune system.

Nir Barzilai on Health Span, Life Span and the New Science of Longevity

Longevity and aging researcher Dr. Nir Barzilai participated in a fireside chat conversation with ISB Co-founder and Professor Dr. Lee Hood. The two renowned scientists talked about Barzilai’s study of 750 centenarians, how aging research has changed over the years, and what exciting developments are coming.

Dr. Andrew Magis: Identifying Markers for Cancer Years Before Diagnosis

By taking detailed measurements of blood and other biological samples, ISB scientists have shown they can identify markers for cancer years before diagnosis. This was the topic of a recent Research Roundtable presentation delivered by Dr. Andrew Magis, Director of Data Science in ISB’s Health Data Science Lab.

Why ISB’s Biobank Is Second to None

ISB has developed a biobank that is second to none. In this video, Dr. Jim Heath gives a behind-the-scenes look at the process of creating a biorepository, from taking the handoff of de-identified patient samples at the clinic to storing the processed samples in a deep-freeze cryo-chamber.

Microbiome and weight loss

Can You Lose Weight? Ask Your Microbiome

The strongest associations with weight loss success or failure – independent of BMI – are found in the genetic capacity of the gut microbiome. These new findings open the door to diagnostic tests that can identify people likely to lose weight with healthy lifestyle changes and those who might need more drastic interventions.

Drs. Jim Heath, Yapeng Su and Jihoon Lee

Metabolic Changes in Plasma and Immune Cells Associated with COVID-19 Severity, May Predict Patient Survival

Researchers from Institute for Systems Biology (ISB), Fred Hutchinson Cancer Research Center and other organizations have uncovered underlying metabolic changes that regulate how immune cells react to COVID-19. These findings are associated with COVID-19 severity and may predict patient survival. The work was published in the journal Nature Biotechnology.

2021 ISB Microbiome Series

2021 ISB Virtual Microbiome Series Announced

Our multi-day microbiome-themed virtual course and symposium is back by popular demand! ISB is hosting a two-day course on October 13 & 14, followed by a symposium on October 15. Both events are virtual and free. The intended audience for these events are graduate students, postdocs, principal investigators, industry scientists, educators, clinicians, or any other variety of microbiome-curious person from across the globe.

Dr. Sean Gibbons Spotlighted in Alumni Profile

MIT’s Center for Microbiome Informatics and Therapeutics recently featured Dr. Sean Gibbons in an alumni profile. Gibbons discussed his academic arc that started in Montana and led to his master’s studies (sponsored by a Fulbright Graduate Fellowship) at Uppsala University in Sweden, completing his PhD in biophysical sciences at the University of Chicago, and conducting his postdoc work in the lab of Eric Alm. He also talked about some of…

Spotlight On Amy Zamora, Former ISB Systems Research Scholar

Between 2018 and 2020, Amy Zamora’s tenure as a systems research scholar allowed her to merge her two interests – math and biology – and to learn a lot more along the way. “I didn’t really know how to combine my passions until I came to ISB,” she said.