Sui Huang's illustration of cancer attractors on the epigenetic landscape

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay

ISB Professor Sui Huang challenges the prevailing view of cancer as purely genetic in a new essay published in PLOS Biology. Huang and colleagues argue that many cancers lack identifiable driver mutations, suggesting non-genetic factors and disrupted gene regulatory networks may play crucial roles in cancer development.

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay
ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay
Drs. Wei Wei and Jim Heath

Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It

ISB researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.

Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It
Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It
Carole Ellison, Donor Spotlight

Carole Ellison’s Bold Bet on Science and the Researchers of Tomorrow

Carole Ellison has supported ISB’s research and STEM programs for over a decade. She established the K. Carole Ellison Fellowship in Bioinformatics, funding groundbreaking research that has enabled young scientists to make critical discoveries.

Carole Ellison’s Bold Bet on Science and the Researchers of Tomorrow
Carole Ellison’s Bold Bet on Science and the Researchers of Tomorrow

New Research Uncovers Hidden Rules of Immune Response

Scientists at the Institute for Systems Biology (ISB) reveal how T cells "decide" their fate in fighting infections like COVID-19, paving the way for improved treatments for infections, cancer, and autoimmune diseases.

New Research Uncovers Hidden Rules of Immune Response
New Research Uncovers Hidden Rules of Immune Response
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