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Researchers at the Institute for Systems Biology argue that combining systems biology, longitudinal multiomics data, and artificial intelligence could transform healthcare from reactive treatment to proactive prevention, enabling scientists and clinicians to detect early molecular signs of disease and intervene before symptoms appear.
From Nobel recognition and scientific firsts to transformative collaborations and community impact, 2025 marked one of the most significant years in ISB’s 25-year history.
Discussing Super Agers, Drs. Eric Topol and Lee Hood connected breakthroughs in genomics, AI, and lifestyle science to the pursuit of longer, healthier lives.
The pioneering work of Mary Brunkow and Fred Ramsdell began with a mysterious mutant mouse known as “scurfy,” leading them to identify the FOXP3 gene and unlock how regulatory T cells prevent autoimmune disease — discoveries that now point to new treatments in cancer and autoimmunity.
In a Research Roundtable presentation and Q&A, ISB President Dr. Jim Heath shared how his team is using generative AI to unlock new understanding of human immunity, and how these discoveries could help predict disease severity, improve cancer therapies, and more.
Scientists at the Institute for Systems Biology (ISB) reveal how T cells “decide” their fate in fighting infections like COVID-19, paving the way for improved treatments for infections, cancer, and autoimmune diseases.