Sui Huang's illustration of cancer attractors on the epigenetic landscape

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay

ISB Professor Sui Huang challenges the prevailing view of cancer as purely genetic in a new essay published in PLOS Biology. Huang and colleagues argue that many cancers lack identifiable driver mutations, suggesting non-genetic factors and disrupted gene regulatory networks may play crucial roles in cancer development.

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay
ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay
Drs. Wei Wei and Jim Heath

Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It

ISB researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.

Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It
Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It

New Research Uncovers Hidden Rules of Immune Response

Scientists at the Institute for Systems Biology (ISB) reveal how T cells "decide" their fate in fighting infections like COVID-19, paving the way for improved treatments for infections, cancer, and autoimmune diseases.

New Research Uncovers Hidden Rules of Immune Response
New Research Uncovers Hidden Rules of Immune Response
Wei

ISB-Developed MetaboCore Offers Precision Cancer Care Faster Than Ever

Dr. Wei Wei has developed a promising new companion diagnostic tool called MetaboCore to help physicians quickly select the most effective systemic therapy for each cancer patient. 

ISB-Developed MetaboCore Offers Precision Cancer Care Faster Than Ever
ISB-Developed MetaboCore Offers Precision Cancer Care Faster Than Ever
ilya shmulevich portrait illustration

Celebrating Professor Shmulevich’s Life and Scientific Contributions

ISB hosted a full-day symposium – titled Resonance – celebrating the life and scientific contributions of Professor Ilya Shmulevich, who passed away in April 2024 from complications of acute myeloid leukemia.

Celebrating Professor Shmulevich’s Life and Scientific Contributions
Celebrating Professor Shmulevich’s Life and Scientific Contributions
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