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The prize recognizes foundational discoveries about regulatory T cells and the FOXP3 gene that redefined immune tolerance and opened avenues to treat autoimmune disease, enable transplantation, and advance immuno-oncology. ISB celebrates Dr. Brunkow’s leadership and collaborative science.
ISB has won a 2025 AWS Imagine Grant to advance Tarpon, a generative AI platform that generates digital fingerprints of T cell receptors. By linking immune signatures to genomic and clinical data, Tarpon enables rapid discovery and the design of targeted therapies.
Discussing Super Agers, Drs. Eric Topol and Lee Hood connected breakthroughs in genomics, AI, and lifestyle science to the pursuit of longer, healthier lives.
The pioneering work of Mary Brunkow and Fred Ramsdell began with a mysterious mutant mouse known as “scurfy,” leading them to identify the FOXP3 gene and unlock how regulatory T cells prevent autoimmune disease — discoveries that now point to new treatments in cancer and autoimmunity.
ISB honors Dr. Charles “Chuck” Watts (1942–2025) – physician, leader, and former Board Chair – who died on September 23 after a battle with esophageal cancer. A champion of patient safety, systems biology, and STEM education, Chuck guided ISB with insight and warmth. His legacy endures in our mission and community.
ISB Co-founder Dr. Leroy (Lee) Hood has been named one of the inaugural recipients of the Michael Sela Prize in Biomedical Sciences, awarded by the Weizmann Institute of Science. Hood shares the honor with Dr. Francis S. Collins and Dr. Eric S. Lander for pioneering work that has reshaped modern medicine and advanced human health.