ISB News

‘Demystifying Disease, Democratizing Health Care’

In the Feb. 26, 2014, issue of Science Translational Medicine, Dr. Lee Hood and Dr. Nathan Price, of Institute for Systems Biology, deliver an editorial stating the vision of the 100K Wellness Project. The project will track health-related data types for 100K individuals longitudinally over the course of 20-30 or more years. "Unsustainable cost increases threaten the global health care system, and further progress is stymied more by societal than…

Tiniest Malfunctions in a Cell Can Cause Devastating Diseases

3 Bullets: ISB researchers are studying peroxisomes, which are cellular organelles that are linked to a rare syndrome that causes progressive organ complications and infant mortality. Peroxisomes have a role in metabolizing and breaking down cellular waste. Because peroxisomes easily change shape and function according to a cell’s needs, a systems approach is necessary to help decipher that complexity. By Dr. Thurston Herricks Dane Tolmie was a 19-month old boy…

Largest Genetics Catalog of Deadliest Brain Tumor Released

  By Varsha Dhankani Glioblastoma multiforme (GBM) is the most common and deadliest of malignant primary brain tumors in adults. Because of its lethality, GBM was selected as the first brain tumor to be sequenced as part of The Cancer Genome Atlas (TCGA), a comprehensive project funded by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI) to map the genomes of more than 25 types…

Publications: A ‘Google Map’ of Human Metabolism

ISB associate professor Nathan Price and Vangelis Simeonidis, a visiting scholar from Luxembourg Centre for Systems Biomedicine (LCSB is a major strategic partner with ISB), contributed to this paper – “A community-driven global reconstruction of human metabolism” – that was published today in Nature Biotechnology. An excerpt describing the collaborative project from a press release is below. An interactive map is forthcoming.   From Medicalxpress.com: “An international consortium of university…