Media Coverage

Reuters highlights ISB’s Mary Brunkow as co-winner of the 2025 Nobel in Physiology or Medicine, spotlighting her mouse-genetics discovery of FOXP3 as the hallmark of regulatory T cells and peripheral immune tolerance – work now powering Treg-based trials and new therapies for autoimmunity, transplantation, and cancer.

A story that maps the road from puzzling autoimmunity to the immune system’s “brakes” – regulatory T cells and FOXP3 – and the moment those clues crystallize into a Nobel morning for Mary Brunkow and collaborators.

Pre-dawn calls meet decades of discovery: a crisp walk through how the immune system’s “brakes” (FOXP3 and regulatory T cells) propelled Mary Brunkow to a Nobel, and what that means for autoimmune care, cancer, and transplants.

STAT News details why Mary E. Brunkow (now at ISB), Fred Ramsdell, and Shimon Sakaguchi won the 2025 Medicine Nobel – discoveries in peripheral immune tolerance (regulatory T cells/FOXP3) that illuminate autoimmunity and inform new therapies.

KING 5 spotlights Seattle’s Mary Brunkow of ISB, newly named 2025 Nobel laureate in Physiology or Medicine. The segment recaps her FOXP3 discovery, from scurfy mouse genetics to regulatory T cells, and captures the hometown reaction as her work shapes therapies for autoimmunity, transplantation, and cancer.

NPR spotlights ISB’s Mary Brunkow, co-recipient of the 2025 Nobel Prize in Physiology or Medicine, tracing her FOXP3 gene discovery from the scurfy mouse to regulatory T cells and immune tolerance, and noting how her work now underpins therapies across cancer, autoimmunity, and transplantation.

The New York Times spotlights ISB’s Mary Brunkow, co-winner of the 2025 Nobel Prize in Physiology or Medicine, emphasizing her gene-discovery work identifying FOXP3 and establishing regulatory T cells as key guardians of immune tolerance – foundational science now informing cancer, autoimmunity, and transplantation therapies.

ISB’s Mary Brunkow, co-winner of the 2025 Nobel Prize in Physiology or Medicine, is highlighted for her gene-discovery work that pinpointed FOXP3 and unlocked regulatory T cells – core to immune tolerance – with origins in scurfy mouse studies and links to human IPEX disease. Includes how she nearly missed Sweden’s call.