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Biochemists and molecular biologists sweep major 2025 honors
October was a banner month for biochemistry and molecular biology, with researchers across the field earning major honors – including a Nobel Prize awarded to Mary Brunkow and discoveries poised to transform medicine.
Seattleite’s Nobel Prize-winning work benefits all humanity
Local achievement with global impact: This editorial highlights how the Nobel Prize awarded to Mary Brunkow and her colleagues extends far beyond Seattle, recognizing groundbreaking work in immune-system regulation that stands to benefit humanity at large.
The origins of tolerance: the 2025 Nobel prize in medicine
The Lancet profiles 2025 Nobel laureates Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi, tracing their decades-long collaboration that uncovered the FOXP3 gene and regulatory T cells – discoveries that transformed understanding of immune tolerance and opened new paths for treating autoimmune and inflammatory diseases.
AP’s race to Nobel winners highlights exclusive access and global collaboration
The Associated Press spotlights its behind-the-scenes work covering the 2025 Nobel Prize, using global collaboration and exclusive access – from a pre-dawn knock at Dr. Mary Brunkow’s door to multimedia teamwork worldwide – to deliver prompt, emotionally charged storytelling.
Nobel Prize in medicine goes to the discovery of the leash of our immune system
In her CBC conversation, Mary Brunkow reflects on the surprise of receiving the 2025 Nobel Prize and the collaborative journey behind her groundbreaking work on immune-system regulation. She recounts how the discovery of the FOXP3 gene – stemming from studies of the “scurfy” mouse model – helped unlock the mystery of how regulatory T cells prevent the body from attacking itself.
Local scientist wakes up to learn she's winner of 2025 Nobel Prize in Medicine
In an in-person interview on KOMO News’ ARC Seattle, Nobel laureate Mary Brunkow recounts the early-morning call from Stockholm and discusses the FOXP3 discovery’s impact.
Nobel Prize winner Mary Brunkow on immune system research
In an interview with NPR’s Here & Now, Dr. Mary Brunkow reflects on the scurfy mouse, finding FOXP3, and the clinical promise of T regs – explained for a general audience in a concise, ~6-minute segment with host Scott Tong.
What's the difference between a scurfy mouse and a scruffy mouse? A Nobel Prize
In this ~20-minute interview, KUOW’s Soundside host Gabriel Spitzer talks with Nobel laureate Mary Brunkow about the “scurfy” mouse, discovering FOXP3, and how her work on immune tolerance is reshaping treatments for autoimmune disease and cancer
Nobel Laureate Dr. Mary Brunkow speaks at a press conference held at ISB on October 7, 2025. (Photo by Alex Garland for ISB)
ISB’s 2025 Nobel Prize Coverage
ISB’s Dr. Mary Brunkow received the 2025 Nobel Prize in Physiology or Medicine for transformative discoveries in immune tolerance.
Visit our Nobel Prize hub page for stories, photos, reactions celebrating this historic achievement, and more.