All News - Institute for Systems Biology (ISB)

Posted: July 24, 2025

New Tool Unlocks Biomedical Discovery with Launch of Biomedical Data Translator

The Biomedical Data Translator is now publicly available, offering a powerful open-source platform that integrates diverse biomedical datasets. Designed to accelerate discovery and patient care, Translator helps users explore complex data and uncover actionable insights with ease.

Posted: June 18, 2025

Microbes That Keep Ecosystems in Balance Can Fall Apart Easily, New Study Finds

Just-published research out of ISB shows the microbial teamwork behind denitrification can collapse in polluted environments, threatening ecosystem balance and resilience.

Posted: May 13, 2025

From 'Genesis' to Reality: Decoding the AI Revolution

Co-Author Craig Mundie and ISB’s Dr. Jim Heath discuss AI’s rapid evolution, ethical considerations, and potential to revolutionize science and society in a compelling Town Hall event.

Posted: April 21, 2025

Celebrating the Life and Legacy of Valerie Logan Hood

ISB is deeply saddened to share the passing of Valerie Logan Hood, beloved wife of ISB Co-founder and Professor Dr. Lee Hood. Her lifelong dedication to K-12 education helped create and shape ISB’s programs, and her influence will be felt for generations to come.

This circular workflow illustrates how personalized medicine is applied using the mmSYGNAL model. Starting with molecular profiling of a new patient, data are mapped to the mmSYGNAL network — originally built from a large patient cohort — and integrated with our MM knowledge base to generate a patient-specific disease network map. This map supports risk prediction and therapy matching, which are synthesized by a Clinical Decision Support Service to provide actionable insights for the treating physician, enabling tailored and informed treatment decisions.

Posted: April 2, 2025

New Model Transforms Multiple Myeloma Risk Prediction

A team of researchers has developed a powerful new tool that could transform how doctors treat multiple myeloma, a complex and often unpredictable blood cancer.

Sui Huang's illustration of cancer attractors on the epigenetic landscape

Posted: March 26, 2025

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay

Sui Huang challenges the prevailing view of cancer as purely genetic in a new essay published in PLOS Biology. Huang and colleagues suggest non-genetic factors and disrupted gene regulatory networks may play crucial roles in cancer development.