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Members of ISB’s Heath Lab and their collaborators have developed a way to sensitively detect and analyze neoantigen-specific T-cell populations from tumors and blood. This promising development may have implications for creating targeted, individual-specific cancer vaccines.
Predicting the alpha diversity of an individual’s gut microbiome is possible by examining metabolites in the blood. The robust relationship between host metabolome and gut microbiome diversity opens the door for a fast, cheap and reliable blood test to identify individuals with low gut diversity.
By using single-cell analysis to measure metabolic activities in rare disseminated tumor cells taken from non-small cell lung cancer (NSCLC) patients, ISB researchers and their collaborators can accurately predict how patients will respond to various cancer therapies, and how treatments will impact a patient’s physiological performance and survival.
ISB’s Dr. Sui Huang uses the theory of complex systems and applies it to cancer research. In this video Q&A, he discusses the cancer paradox and highlights the importance of understanding the mechanism of why cancer treatments can backfire in order to open a new avenue for therapy and treatments.
Pregnancy is a biological necessity for survival. Traditionally, however, our knowledge about pregnancy and pregnant women have lagged. Dr. Alison Paquette, a research scientist in ISB’s Hood-Price Lab, hosted a video question-and-answer session where she discussed pregnancy, the placenta, preterm birth, and much more.
About 75 people attended “Reimagine,” ISB’s annual fundraiser, and contributed nearly $35,000 to accelerate groundbreaking research. The event was held at The Ruins, and featured presentations by legendary biologist and ISB Co-founder Dr. Lee Hood and renowned scientist and ISB President Dr. Jim Heath.