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A New Approach to Alzheimer’s Disease
The impact of Alzheimer’s Disease is staggering – 6 million Americans diagnosed, a financial toll of $600 billion annually, and no effective drug treatments. ISB Co-founder Dr. Lee Hood said the traditional approach isn’t working, and we need to think about it in brand new ways.
Bile Acids Provide More Evidence of the Gut Microbiome’s Effect on Alzheimer’s Disease
ISB researchers and their collaborators are looking beyond the one-drug, one-solution approach that has thus far failed in Alzheimer’s disease research. Instead, they are focusing on other promising research avenues, such as the possible role of the gut microbiome in dementia.
Brain Health & Research Institute Enters Scientific Partnership with ISB
Brain health expert Dr. Mary Kay Ross announced the creation of the Brain Health & Research Institute (BHRI) in Seattle, and a scientific collaboration with ISB. Through that partnership, BHRI will blend the practical application of medical therapies and treatment protocols with ten advanced scientific analysis now available through personalized medicine and computational biology.
Clinical Trial Explores the Effects of Health Coaching on Cognitive Function in Patients with Early-Stage Alzheimer’s
Institute for Systems Biology (ISB) is among several organizations conducting a clinical trial testing how health coaching affects the cognitive function of patients with early-stage Alzheimer’s disease and analyzing longitudinal, multi-omic data to explore transitions in cognitive function over time.
NIH-Led Effort – Including ISB – Launches Big Data Portal for Alzheimer’s Drug Discovery
The National Institutes of Health announced the launch of a new Alzheimer’s Big Data portal, which includes the first wave of data for use by the research community. This portal is the result of the Accelerating Medicines Partnership (AMP) program, which focuses on facilitating collaboration among government agencies, academia and industry in order to translate research more quickly to therapies. The launch of the AMP Alzeheimers Disease Knowledge Portal is…
NIH Awards $45M to Alzheimer’s Research
The National Institutes of Health announced $45 million in grants to support several research groups that are focused on Alzheimer's prevention. ISB's Price Lab will be working with the University of Florida to use systems biology to identify new therapeutic targets in the innate immune system. The systems approach, which ISB pioneered, allows scientists to integrate and analyze disparate data (genome, gene expression, pathology) in order to find the molecular…
$500K Proof of Concept Grants Awarded to ISB Scientists
Photo: ISB’s Jennifer Smith speaks to Jose Banda, superintendent of Seattle Public Schools, in this archived photo. Jennifer just received a $250,000 grant from the Life Sciences Discovery Fund. The Life Sciences Discovery Fund announced the recipients of $1.25 million in Proof of Concept grants. ISB’s Brady Bernard, of the Shmulevich Group, and Jennifer Smith, of the Aitchison Group, each will receive grants totaling almost $500,000. From the LSDF press…