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The impact of Alzheimer’s Disease is staggering – 6 million Americans diagnosed, a financial toll of $600 billion annually, and no effective drug treatments. ISB Co-founder Dr. Lee Hood said the traditional approach isn’t working, and we need to think about it in brand new ways.
ISB researchers examined the associations between the gut microbiomes of about 3,400 people and roughly 150 host characteristics. The team looked at diet, medication use, clinical blood markers, and other lifestyle and clinical factors, and found evidence that variations of the gut microbiome are associated with health and disease.
There is a dichotomy between Bacteroides- and Prevotella-dominated guts — two common gut bacterial genera — and there is a significant barrier when it comes to transitioning from one to the other.
Dr. Nathan Price has been inducted into the American Institute for Medical and Biological Engineering’s (AIMBE) College of Fellows. Price was nominated, reviewed, and elected by peers and members of the College of Fellows for his contributions deriving medical and biological insights from large-scale data analysis and network modeling, and translating those insights to society.
Letter from the president: Dr. Jim Heath announces the kickoff of a 2020 celebration marking ISB’s 20th anniversary. The year-long celebration will include an ISB-Town Hall Seattle speaker series focusing on some of the most important topics in science and health care.
Researchers at ISB harnessed deep molecular and physiological information to determine an individual’s biological age, which they found was reflective of overall health compared to chronological age. The findings were published in the Journals of Gerontology: Series A.
We created a new brand identity — including logo and tag line — to reflect ISB’s evolution since our inception in 2000, and ahead of our 20th anniversary. ISB is proud to be a part of the vibrant research community in Seattle, and is committed to translational and collaborative science.
About 75 people attended “Reimagine,” ISB’s annual fundraiser, and contributed nearly $35,000 to accelerate groundbreaking research. The event was held at The Ruins, and featured presentations by legendary biologist and ISB Co-founder Dr. Lee Hood and renowned scientist and ISB President Dr. Jim Heath.
In a public panel discussion put on by Town Hall Seattle and ISB, legendary biologist Dr. Lee Hood, PSJH Chief Clinical Officer Dr. Amy Compton-Phillips, and PATH’s Program Leader of Diagnostics Tala de los Santos addressed the promise — and challenges — of implementing and practicing 21st century health care.
In the two decades since joining Dr. Lee Hood as a postdoc, Dr. Qiang Tian has made a tremendous impact on ISB’s science and culture. March 31 is his final day at ISB, as he is returning to China and joining Shanghai’s National Research Center for Translational Medicine.
ISB President Dr. Jim Heath and ISB Co-founder Dr. Lee Hood are prominently featured in a new podcast created by Ozy, the popular news website. The podcast is called “The Future of X.” In the series’ first episode, Heath and Hood discuss cancer immunotherapy, personalized health care, and more.
“Scientific wellness” should be widely adopted as a health strategy to avoid chronic illnesses and reduce health care costs, said ISB co-founder Dr. Lee Hood, speaking at the “Schrödinger at 75 conference” on the future of biology, in Dublin. Hood’s presentation was covered by The Irish Times.
Philanthropist Carole Ellison created the recently unveiled K. Carole Ellison Fellows in Bioinformatics. “It’s so exciting to be part of (young researchers’) lives and help them along in their careers,” Ellison said.
“Another vision for health care is emerging — one that is focused on wellness rather than disease; one that is proactive instead of reactive; one that takes a systems approach to biology and medicine rather than studying one gene, one cell or one protein at a time.” Read this Psychology Today story penned by ISB’s Lee Hood and Nathan Price.
“Excessive spending and poor outcomes in health care and drug development necessitate the search for new research paradigms to translate cutting-edge, scientific discoveries of systems medicine into the clinic more quickly and efficiently.” ISB’s Kalliopi Trachana and colleagues, wrote “Taking Systems Medicine to Heart,” which was published in Circulation Research.
ISB’s compass has always been oriented toward the future. Even when we reflect on the past year for each annual report, it’s always through the lens of what’s on the horizon. We are remarkably consistent in that regard, which is in no small part due to our president Dr. Lee Hood, whose vision is perpetually a decade – at least – ahead of everyone else.
Institute for Systems Biology and Arivale “Pioneer 100 Study” is featured on the cover of August’s Nature Biotechnology. The artwork was created by ISB’s Associate Director of Communications Allison Kudla in collaboration with contributing author John C. Earls, software engineer in Hood/Price Lab.