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A photograph depicting a woman in a sparkling ballgown shaking hands with a man in a tuxedo on a stage with standing dignitaries behind them.
ISB’s Dr. Mary Brunkow Wins 2025 Nobel Prize in Physiology or Medicine
ISB Named Winner of 2025 Amazon Web Services Imagine Grant for Nonprofits  
Graphic showing Dr. Lee Hood, left, and Dr. Eric Topol.
Eric Topol and Lee Hood — Two Scientific Luminaries on Longevity and Prevention
Innovation District Building
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About ISB

Institute for Systems Biology (ISB) is a collaborative and cross-disciplinary non-profit biomedical research organization based in Seattle. We focus on some of the most pressing issues in human health, including aging, brain health, cancer, COVID-19, as well as many infectious diseases. Our science is translational, and we champion sound scientific research that results in real-world clinical impacts. ISB is an affiliate of Providence, one of the largest not-for-profit health care systems in the United States.