ISB News

SYSTEMS BIOLOGY 101: On Being Interdisciplinary

In describing systems biology and the distinguishing characteristics of ISB’s approach, we always emphasize how our lab groups are intentionally and necessarily interdisciplinary. One of our labs, for example, includes molecular biologists, microbiologists, geneticists, engineers, oceanographers, and even an astrophysicist. The complexity of biology in this age of “big data” requires diverse teams in order tackle such vast amounts of data and to make sense of it all. New technologies that crunch data faster and more efficiently also permit researchers to re-analyze existing datasets, a process which often reveals undiscovered information. Complementary skills empower any of our groups of researchers to better understand biological or environmental challenges from different perspectives and to arrive at shareable insights more quickly. Our interdisciplinary teams have contributed notable advances to everything from ocean acidification to neurodegenerative diseases and tuberculosis to multiple cancers.

Recent Articles

  • Wei Wei, PhD

    Dr. Wei Wei Promoted to Associate Professor

    Wei Wei, PhD – an accomplished cancer researcher with expertise in biotechnology and cancer systems biology – has been promoted to ISB associate professor. The Wei Lab focuses on understanding how cancer cells adapt to therapeutic treatment to foster therapy resistance by coordinating their internal molecular machinery and how these adaptive changes evolve within diverse tumors influenced by the tumor microenvironment. 

  • Drs. Nitin Baliga and James Park

    How Glioblastoma Resists Treatment – and Ways to Prevent It

    Glioblastoma is one of the deadliest and most aggressive forms of primary brain cancer in adults and is known for its ability to resist treatment and to recur. ISB researchers have made breakthrough discoveries in understanding the mechanisms behind acquired resistance, focusing on a rare and stubborn group of cells within tumors called glioma stem-like cells.

  • Hack Your Health: An Evening with Anjali Nayar and Dr. Sean Gibbons

    Netflix’s “Hack Your Health: The Secrets of Your Gut” is a documentary that merged gut microbiome experts, four individuals – including a well-known hot dog eating champion – facing personal battles with gastrointestinal health, and a unique, effective visual method of “showing” the gut microbiome in action.