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Adding lifestyle coaching to treatment decreases cognitive decline in early Alzheimer’s
McKnights Senior Living published a news story detailing results from the ISB-led Coaching for Cognition in Alzheimer’s (COCOA) trial showing that supplementing the standard of care for early-stage Alzheimer’s disease with lifestyle coaching leads to less cognitive decline.
Computer Model Identifies Which Species Are Important in a Healthy Microbiome
ISB researchers collaborated on an international research project that found a way to determine which species in the gut are important and how they interact to create a healthy microbiome.
A systems biology perspective on the gut microbiome
ISB Associate Professor Dr. Sean Gibbons was a guest on the ISAPP Science, Microbes & Health podcast. In this episode, Gibbons talked about exploring and manipulating the complex ecology of the microbiome with the aim of engineering outputs of this system, as well as the utility of AI in microbiome science and how the microbiome will play a role in personalized medicine in the future, including in the delivery of probiotics and prebiotics.
Breakthrough Study: Alzheimer’s Patients Benefit From Lifestyle Coaching, Not Drugs
The ISB-led prospective randomized controlled trial called COCOA – Coaching for Cognition in Alzheimer’s – showed that supplementing personalized coaching along with the standard of treatment leads to less cognitive decline in early-stage Alzheimer’s patients than standard of care alone.
Long COVID: An explainer and research roundup
The Journalist’s Resource featured work by ISB researchers showing four predictive factors of long COVID. The Journalist’s Resource was created by Harvard Kennedy School’s Shorenstein Center on Media, Politics and Public Policy as an open-access online publication for journalists.
What the young can give to the old
The Economist highlights work by several ISB researchers showing that gut microbiome patterns reflect healthy aging and predict survival in humans. The work was originally published in the scientific journal Nature Metabolism.
The Next Revolution In Medicine: Scientific Wellness, AI And Disease Reversal
Lee Hood and Nathan Price were guests on the Doctor’s Farmacy podcast, and spoke with Dr. Mark Hyman about the future of personalized healthcare through scientific wellness, how AI is changing the medical industry, and much more.
How Assessing Biological Age Improves Wellness
Lee Hood and Nathan Price discuss their approach to scientific wellness – distilling data into a simple, actionable measurement: biological age. Their goal is to leverage technology to compile data from the brain, body, gut microbiome, and more to create a model for scientific wellness.
Nobel Laureate Dr. Mary Brunkow speaks at a press conference held at ISB on October 7, 2025. (Photo by Alex Garland for ISB)
ISB’s 2025 Nobel Prize Coverage
ISB’s Dr. Mary Brunkow received the 2025 Nobel Prize in Physiology or Medicine for transformative discoveries in immune tolerance.
Visit our Nobel Prize hub page for stories, photos, reactions celebrating this historic achievement, and more.