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How Many Times Should You Poop A Day?
Infrequent pooping may be setting yourself up for medical problems down the road, and pooping too often brings its own issues. Research out of the Gibbons Lab details the “Goldilocks” zone.
Gut Microbes Could One Day Be Deployed to Tackle Sleepless Nights
Personalized pre/probiotic treatments could someday be used to support healthy sleep through stressful exam periods and menopause, a new review by Gibbons Lab scientists suggests.
How Cancer Cells Quickly Learn to Dodge a Key Drug
Research from the Heath and Wei labs has uncovered the rapid cellular mechanisms that melanoma cells employ to develop resistance to the cancer drug vemurafenib. By closely examining the initial hours and days after drug exposure, the study reveals how cancer cells activate a backup communication system to bypass the drug’s effects, suggesting potential new combination treatment strategies to overcome this resistance.
Skip the Dietary Questionnaire, Use Stool to Track What You Eat
We eat things that contain DNA – plants, fungi, animals – and some of that DNA survives passage through the gut. So the Gibbons Lab decided to measure that DNA directly to find out what people tracking their food were actually eating.
How Bowel Frequency Impacts Your Health
Sean Gibbons was interviewed on “The Excerpt,” the flagship podcast of USA TODAY, and discussed his research looking at poop frequency and its implication on health.
Key Mechanism Behind Melanoma’s Early Resistance to BRAF Inhibitors Identified
Work out of the Heath and Wei labs identified a survival mechanism that allows melanoma cells to quickly evade BRAF inhibitor treatments, and a reversible adaptation that can occur within hours of the first treatment and does not rely on reactivating the BRAF-ERK pathway.
Racing Against Time: Melanoma Develops Resistance to Treatment Within Hours
The Wei and Heath labs and collaborators from MIT have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.
Rethinking Cancer: Moving Beyond Genetic Mutations to a Holistic View
Sui Huang challenges the prevailing view of cancer as purely genetic. Huang and colleagues argue that many cancers lack identifiable driver mutations, suggesting non-genetic factors and disrupted gene regulatory networks may play crucial roles in cancer development.