COVID and Long COVID
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By integrating single-cell, proteomic, genetic, clinical, and laboratory data, the team found that these cells adopt molecular features also seen in established autoimmune diseases. The findings help explain how viral infections can disrupt immune regulation and may provide a framework for understanding and eventually preventing autoimmune complications following infection.
Researchers at the Institute for Systems Biology have developed a powerful new platform that can identify and deeply profile antigen-specific CD4+ T cells at unprecedented scale and resolution. Published in Nature Communications, the work could help accelerate vaccine design, improve immune monitoring, and advance next-generation cancer immunotherapies.
Whitney Gibb used to move through life at full speed. After COVID, brain fog, fatigue, and memory loss reshaped her daily life — offering a powerful window into the realities of Long COVID and the research now working to understand it.
At a recent virtual town hall, leaders of the Pacific Northwest RECOVER hub shared what they’ve learned so far about long COVID — from symptom trajectories and genetic risk to early trial results and upcoming studies — and answered questions from participants about risk factors, persistent symptoms and what comes next.
Researchers from the NIH-funded RECOVER study shared new insights on the risks of Long COVID, autoimmune links, and upcoming clinical trials during ISB’s July Town Hall.
Scientists at the Institute for Systems Biology (ISB) reveal how T cells “decide” their fate in fighting infections like COVID-19, paving the way for improved treatments for infections, cancer, and autoimmune diseases.