ISB News

Town Hall Seattle panel

Expert Panel Discusses 21st Century Health at Town Hall Seattle Event

In a public panel discussion put on by Town Hall Seattle and ISB, legendary biologist Dr. Lee Hood, PSJH Chief Clinical Officer Dr. Amy Compton-Phillips, and PATH’s Program Leader of Diagnostics Tala de los Santos addressed the promise — and challenges — of implementing and practicing 21st century health care.

Dr. Wei Wei Joins ISB Faculty

Prior to joining ISB’s faculty, Dr. Wei Wei earned his Ph.D. from Caltech and served as a faculty member at UCLA Medical School. In this Q&A, Wei discusses his research career to date, how research might change over the next decade, and much more.

Lee Hood Gives P4 Medicine Talk at University of Michigan

Dr. Lee Hood gave the keynote talk at the 9th Annual Prechter Lecture at the University of Michigan on Nov. 2. Here he speaks about P4 medicine and scientific wellness as it relates to bipolar disease. Link to Video on YouTube  (The talk begins about 40 minutes into the video.)

Infographic showing types of data

‘Integrating big data and actionable health coaching to optimize wellness’

The journal BioMed Central Medicine published a commentary by Dr. Lee Hood, Dr. Jennifer Lovejoy, and Dr. Nathan Price on the Hundred Person Wellness Project – phase 1 of the 100K Wellness Project. The article was published on Jan. 9, 2015. ABSTRACT: “The Hundred Person Wellness Project (HPWP) is a 10-month pilot study of 100 ‘well’ individuals where integrated data from whole-genome sequencing, gut microbiome, clinical laboratory tests and quantified…

ISB’s 100K Project A Top Story on GenomeWeb

By ISBUSA GenomeWeb announces 2014’s top-10 most-read articles on personalized medicine and the article on ISB’s 100K Wellness Project was No. 1. Here’s an excerpt from GenomeWeb’s Jan. 5 story: NEW YORK (GenomeWeb) – GenomeWeb readers in 2014 were most interested in a story about a large study investigating why some people remain healthy while others get sick. The top article was about healthcare entrepreneur Leroy Hood’s efforts to advance…

Dana Riley Black, Director of ISB's Logan Center for Education, and the Rev. Jesse Jackson at the Washington STEM Summit on Dec. 2, 2014.

Talking STEM Education with the Rev. Jesse Jackson

It’s a fine day when the Rev. Jesse Jackson is the surprise guest speaker – after Gov. Jay Inslee – at an event. Dana Riley Black, Director of ISB’s Logan Center for Education, had the opportunity to meet the Rev. Jesse Jackson after his speech during the Washington STEM Summit, which is an annual event to bring education, business and community leaders together for a statewide effort to advance excellence,…

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Xconomy.com Features 100K Project

Xconomy featured an article about the 100K Wellness Project. The article provides an introduction and follows with a Q&A with Dr. Nathan Price, who is Associate Director of ISB. Read the article by Alex Lash, Xconomy.com’s National Biotech Editor: “100K” Marathon: A Decades-Long Health Study Makes Its Business Case

Analyzing Family Genomics Reveals New Culprit in Rare Disease

3 Bullets: Adams-Oliver syndrome (AOS) is a rare congenital disease characterized by scalp lesions and limb defects. Additional vascular abnormalities and heart defects can lead to early death in some patients. By analyzing twelve families affected with the disease, we identified causal mutations in a new disease gene, NOTCH1, in five families. NOTCH1 is likely to be the major cause of AOS. NOTCH1 codes for a transcription factor that governs…

Cover image for ISB's 2013 Annual Report.

ISB’s 2013 Annual Report is Now Available

Institute for Systems Biology has a dizzying breadth of research projects. But when we talk about what we do, it’s how we do it that matters most. The systems approach that we pioneered and exemplify continues to distinguish our ability to tackle the most complex biological and environmental challenges today. Because of how we apply our hallmark collaborative, cross-disciplinary and integrative approach, our collective success is greater than the sum…

ISB's Ilya Shmulevich describes his lab's work in The Cancer Genome Atlas project and how ISB and FHCRC could collaborate.

Melding ISB and FHCRC Brain Power for Cancer Research

(Photo above: ISB’s Dr. Ilya Shmulevich describes his lab’s work in The Cancer Genome Atlas project and how ISB and FHCRC could collaborate.) Big health challenges require big science. Cancers are prime examples of overwhelmingly complex diseases that need the power of a cross-disciplinary, systems biology approach to decipher the underlying dysfunctional gene networks in order to find ways to prevent and manage the diseases and develop more effective therapies….

100K Wellness Project article in Clinical Omics written by ISB's Lee Hood and Nathan Price.

100K Wellness Project Article by Lee Hood and Nathan Price in Clinical Omics

The latest press about the 100K Wellness Project is in the May 15 issue of Clinical Omics and features a piece by Dr. Lee Hood, president of Institute for Systems Biology (ISB), and Dr. Nathan Price, ISB’s associate director. Read “Promoting Wellness and Demystifying Disease: The 100K Project”

Summer Course Registration Is Now Open!

Summer Course: Systems Biology of Disease Register Now Offered by Institute for Systems Biology and Center for Systems Biology Course Objective The goal of this course is to introduce the core concepts of systems biology and their application to systems biomedicine. We will demonstrate the importance of cross-disciplinary interactions for the success of systems biology programs. When July 28 – August 1, 2014 9 am to 5 pm Where Institute…

Mark Calendars for Dr. Lee Hood’s Reddit AMA on April 11

Dr. Lee Hood will participate in a Reddit AMA (Ask Me Anything) on March 24 April 11 from 10-11 a.m. PST. There will be more details posted on Reddit.com the morning of April 11. For now, feel free to look at the list of upcoming science AMAs or check out some previous science AMAs here.

The New York Times Science Times Podcast: Dr. Lee Hood and 100K Wellness Project

The New York Times's Jeffrey DelViscio, who is a senior staff editor for the Science Times, interviewed our Dr. Lee Hood during the recent (Feb. 13-17) American Association for the Advancement of Science conference in Chicago for a podcast segment called "The Virtual Self." From the introduction: "…in order to truly understand health, wellness and disease, an individual human must create he or her own data cloud, which can be…

ISB Has Two New Patents

2014 is off to a great start for innovation in human health. ISB released two new patents in January that will make great contributions to personalized medicine. One of the patents, issued on January 27 and titled Use of Gene Expression Signatures to Determine Cancer Grade, has ISB President Dr. Lee Hood and ISB Senior Research Scientist Qiang Tian listed as inventors. Also sharing in that patent is Xiaowei Yan…

Lee Hood at World Stem Cell Summit

Genetic Engineering & Biotechnology News offered some highlights from the World Stem Cell Summit, where ISB president, Dr. Lee Hood, gave today's keynote talk: “In 5 to 10 years, you will have your genomes as part of your medical records,” Leroy Hood, M.D., Ph.D., Institute for Systems Biology, told attendees of the World Stem Cell Summit 2013 today, in San Diego. “Third-generation sequencing will be revolutionary,” he said in his…

Why Does Lee Hood Travel So Much? He’s a Man on a Mission

Dr. Lee Hood believes that ISB scientists are missionaries who are spreading the power of systems biology. He is always on the road and today (June 24) he’s in Lyon, France, to attend the EISBM Symposium 2013 to give a talk on P4 medicine. Prior to arriving in Lyon, Lee was in Jerusalem to give a talk at the Israeli Presidential Conference, which drew world leaders such as Bill Clinton…

Luxembourg-ISB Partnership: ‘An Unqualified Success’

By Hsiao-Ching Chou LUXEMBOURG JOURNAL, June 12, 2013 – At the 17th-century Neumünster Abbey, the cultural heart of Luxembourg City, a small group of some of the world’s most cutting-edge scientists gathered on June 10-11, 2013, for a symposium to discuss the future of medicine and healthcare. The consensus was clear: Achieving the greatest advances requires “no-box” thinking, cross-disciplinary teamwork and, as ISB president, Dr. Lee Hood, likes to say,…