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ISB Creates PerSort, a New Cell Sorting Technology Aimed at Studying Tuberculosis
ISB researchers Dr. Nitin Baliga, Dr. Eliza Peterson and Dr. Vivek Srinivas have developed a new cell sorting technology, called PerSort, that isolates and characterizes dormant persisters that exist in cultures of Mycobacterium tuberculosis, the pathogen that causes tuberculosis.
Unveiling the Guerrilla Warfare Tactics of Mycobacterium Tuberculosis
ISB researchers have unveiled new insights on how Mycobacterium tuberculosis, the pathogen that causes tuberculosis, enters and exits a dormant state in human hosts. About a quarter of the world’s population has latent TB, so these important findings will enable and accelerate the discovery of more effective TB drugs.
Bio-Fiction Recap
On May 7, ISB hosted the first-ever screening of BIO·FICTION in North America. More than 120 people attended the event, which took place as part of the South Lake Union Art Walk. BIO·FICTION explores the emerging field of synthetic biology from different disciplinary angles including science and engineering, social science, cultural studies, amateur biology, filmmaking, art and design. The original program had presentations, panel discussions, do-it-yourself biology demos, performances, art…
New Open-Access Multiscale Model Captures Dynamic Molecular Processes in Unprecedented Detail
3 Bullets: Microbes are efficient because their streamlined genomes allow them to evolve and adapt rapidly to complex environmental changes. Decoding the highly-compressed information within a microbial genome requires sophisticated systems biology tools to map the genetic programs, and understand how they are executed. ISB researchers invented novel algorithms to unzip and decode microbial genomes into the EGRIN 2.0, an open-access multiscale model that captures instructions for executing the dynamic…
ISB’s 2013 Annual Report is Now Available
Institute for Systems Biology has a dizzying breadth of research projects. But when we talk about what we do, it’s how we do it that matters most. The systems approach that we pioneered and exemplify continues to distinguish our ability to tackle the most complex biological and environmental challenges today. Because of how we apply our hallmark collaborative, cross-disciplinary and integrative approach, our collective success is greater than the sum…
Guest Post: Harvard at ISB
Guest Post By Alia Qatarneh Research Assistant, Life Sciences Outreach Program Harvard University The realm of research is changing. The understanding of a scientific phenomenon is no longer a journey on a one-way road. It is an active collaboration between many departments, professionals, and experts, resulting in interdisciplinary frameworks that can tackle the vast principles of biology. Systems biology combines those aspects and allows for the exploration of how components…
ISB in Antarctica: Researcher Receives Medal
Allison Lee, who traveled to Antarctica this spring aboard a research cruise on an icebreaker in the Ross Sea, just received an Antarctic Service Medal for her participation. The medal was created by Congress and presented by the National Science Foundation to those who serve on a U.S. expedition to Antarctica. Allison is a member of the Nitin Baliga Lab and has been working closely with senior research scientist Mónica Orellana,…
How Systems Biology Can Help Improve ‘Green Crude’ – aka Algae Fuel
Sapphire Energy and ISB today announced a partnership that will lead to exciting discoveries in commercial algae fuel production. You can read the release here. But to hear directly from Dr. Nitin Baliga, who is ISB's Director for Integrative Biology, on why this partnership is unique, watch this short interview.