By analyzing blood plasma samples taken at several time points, ISB researchers have identified specific proteins that persistently presented as outliers and signaled metastatic cancer well before patients were diagnosed. The findings were published in the journal Scientific Reports.
Researchers at ISB harnessed deep molecular and physiological information to determine an individual’s biological age, which they found was reflective of overall health compared to chronological age. The findings were published in the Journals of Gerontology: Series A.
Dr. Nathan Price has been promoted to full professor. He started at ISB as an associate professor in the fall of 2011. Dr. Price also serves as the associate director of ISB and co-PI of the 100K Wellness Project. Congratulations! Learn more about the Price Lab and some of his group’s publications. ISB staff gathered to toast Dr. Price on March 26, 2015:
The journal BioMed Central Medicine published a commentary by Dr. Lee Hood, Dr. Jennifer Lovejoy, and Dr. Nathan Price on the Hundred Person Wellness Project – phase 1 of the 100K Wellness Project. The article was published on Jan. 9, 2015. ABSTRACT: “The Hundred Person Wellness Project (HPWP) is a 10-month pilot study of 100 ‘well’ individuals where integrated data from whole-genome sequencing, gut microbiome, clinical laboratory tests and quantified…
3 Bullets: Mycobacterium tuberculosis (MTB) infects more than 1.5 billion people worldwide partly due to its ability to sense and adapt to the broad range of hostile environments that exist within hosts. To study how MTB controls its responses at a molecular level, ISB researchers and their collaborators at Seattle Biomed perturbed almost all MTB transcription factor regulators and identified the affected genes. This comprehensive map of molecular switches in…
Above: Cover of the November 2014 issue of Real Simple Magazine A team at ISB has been working on the 100K Wellness Project, which you read about here. The November issue of Real Simple Magazine has a feature story on “What Exactly is Wellness?” It includes a mention of our wellness study and a comment from Dr. Nathan Price, ISB associate director. “Perhaps one reason why wellness programs aren’t yet…
Xconomy featured an article about the 100K Wellness Project. The article provides an introduction and follows with a Q&A with Dr. Nathan Price, who is Associate Director of ISB. Read the article by Alex Lash, Xconomy.com’s National Biotech Editor: “100K” Marathon: A Decades-Long Health Study Makes Its Business Case
Institute for Systems Biology has a dizzying breadth of research projects. But when we talk about what we do, it’s how we do it that matters most. The systems approach that we pioneered and exemplify continues to distinguish our ability to tackle the most complex biological and environmental challenges today. Because of how we apply our hallmark collaborative, cross-disciplinary and integrative approach, our collective success is greater than the sum…
The latest press about the 100K Wellness Project is in the May 15 issue of Clinical Omics and features a piece by Dr. Lee Hood, president of Institute for Systems Biology (ISB), and Dr. Nathan Price, ISB’s associate director. Read “Promoting Wellness and Demystifying Disease: The 100K Project”
WHAT YOU SAW IN THE NEWS: Pacific Standard Magazine published the following cover story in September 2013: The Social Life of Genes “Your DNA is not a blueprint. Day by day, week by week, your genes are in a conversation with your surroundings. Your neighbors, your family, your feelings of loneliness: They don’t just get under your skin, they get into the control rooms of your cells. Inside the new…
The National Institutes of Health announced $45 million in grants to support several research groups that are focused on Alzheimer's prevention. ISB's Price Lab will be working with the University of Florida to use systems biology to identify new therapeutic targets in the innate immune system. The systems approach, which ISB pioneered, allows scientists to integrate and analyze disparate data (genome, gene expression, pathology) in order to find the molecular…
ISB associate professor Nathan Price and Vangelis Simeonidis, a visiting scholar from Luxembourg Centre for Systems Biomedicine (LCSB is a major strategic partner with ISB), contributed to this paper – “A community-driven global reconstruction of human metabolism” – that was published today in Nature Biotechnology. An excerpt describing the collaborative project from a press release is below. An interactive map is forthcoming. From Medicalxpress.com: “An international consortium of university…
ISB is proud to announce that Sriram Chandrasekaran, one of our predoctoral scientists in the Nathan Price group, has received one of 10 Harvard Junior Fellowships. This prestigious fellowship grants Sriram the opportunity to pursue an independent research project without the pressure of having to secure funding and with mentoring from faculty at Harvard and MIT. It’s a “sexy way of transitioning to a tenure-track faculty position.” The rigorous interview…
