FOR IMMEDIATE RELEASE SEATTLE, WA and FALLS CHURCH, VA, Sept. 23, 2015—The Institute for Systems Biology (ISB) and the Inova Translational Medicine Institute (ITMI) announced today a new release of Kaviar, the most comprehensive collection of human genomic variants currently available to the public. This release expands on the January 2015 release most notably by the addition of 3842 whole genome sequences provided by ITMI. Inova, a not-for-profit healthcare system…
3 Bullets: Kaviar is ISB’s comprehensive catalog of human genomic variation Kaviar combines 31 data sources for a total of 151 million single nucleotide variants (SNVs), covering 5% of all the positions in the human genome A researcher studying possible disease-causing variants can use Kaviar to answer the question, “Have these variants been observed before, and if so, how often?” By Terry Farrah A typical pair of human genomes are…
The figure above is part of a four-step procedure for the multiscale segmentation of genomic signals. 3 Bullets: Understanding systems from a multiscale perspective gives us a more detailed and holistic view of how features or functions from each scale connect and interact in a given system. The challenge is integrating the different types of information that come from each scale in an efficient way that yields the most insight….
