ISB News

New Tool Uses 3-D Protein-DNA Structures to Predict Locations of Genetic ‘On-Off’ Switches

3 Bullets: Novel systems approach uses high-resolution structures of protein-DNA complexes to predict where transcription factors (genetic switches) bind and regulate the genome. This approach can help researchers better understand and predict binding sites for non-model organisms or ‘exotic’ species. Having such insight and predictive capabilities is critical for reverse- and forward-engineering organisms that could be pivotal for new green biotechnologies. By Jake Valenzuela and Justin Ashworth Researchers at the…