ISB News

Pioneer 100 Study

Institute for Systems Biology and Arivale “Pioneer 100 Study” Establishes Foundation for New Industry of Scientific Wellness

Institute for Systems Biology and Arivale “Pioneer 100 Study” Establishes Foundation for New Industry of Scientific Wellness. Personal, dense, dynamic data clouds enable novel insights into mechanisms of wellness and disease, new approaches to biomarker discovery, and the empowerment of individuals to enhance their own health.

Dr. Jim Heath

Institute for Systems Biology Recruits Technology Pioneer James Heath as President

FOR IMMEDIATE RELEASE >> Renowned scientist, visionary leader from Caltech will join Seattle research community SEATTLE, APRIL 3, 2017 – The Institute for Systems Biology has named James Heath, PhD, as its new president, effective January 2018. Heath is widely recognized as one of the world’s most accomplished scientists, working on fundamental problems at the interface of the chemical, physical, biological, and biomedical sciences, with focus areas of molecular biotechnologies…

Sanger Institute’s COSMIC database expands cancer cloud capabilities at the Institute for Systems Biology

The Wellcome Trust Sanger Institute released this news on Feb. 20, 2017. See original release… FOR IMMEDIATE RELEASE The Wellcome Trust Sanger Institute’s Catalog of Somatic Mutations in Cancer (COSMIC) team announces a new agreement to provide their data to the U.S.-based Institute for Systems Biology (ISB). COSMIC is an expert-curated cancer mutation database, and is the world’s largest and most comprehensive resource for exploring the impact of somatic mutations…

Comprehensive study of esophageal cancer reveals several molecular subtypes, provides new insight into increasingly prevalent disease

The Cancer Genome Atlas Research Network recommends clinical trials organizers and drug manufacturers focus on newly discovered molecular subtypes GRAND RAPIDS, Mich., Jan. 4, 2017 –– A comprehensive analysis of 559 esophageal and gastric cancer samples, collected from patients around the world, suggests the two main types of esophageal cancer differ markedly in their molecular characteristics and should be considered separate diseases. The study, published today in Nature from The…

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ISB Gets $3.4M NIH Extension for Cancer Genomics Cloud

FOR IMMEDIATE RELEASE ISB Receives $3.4 Million Extension to NIH Contract to Continue Development of ‘Cancer Genomics Cloud’ with Google and CSRA SEATTLE, Oct. 21, 2016 – Institute for Systems Biology (ISB) has received a $3.4 million, one-year extension to an existing federally-funded contract from the National Cancer Institute (NCI), National Institutes of Health (NIH). This follows the completion of the initial two-year, $6.5 million contract during which ISB developed…

Wilke Cohen Lyme Disease Project Receives $3M from the Steven & Alexandra Cohen Foundation

PRESS RELEASE Total Funding Has Reached $6.1 Million ISB Researchers Have Discovered Potential Biomarkers and Successfully Reproduced the Borrelia Bacteria in the Lab SEATTLE – June 1, 2016 – Institute for Systems Biology (ISB) has received a transformational, multi-year pledge from the Steven & Alexandra Cohen Foundation to support the Wilke Cohen Lyme Disease Project. In addition to an initial $3.1 million in funding from Jeff and Liesl Wilke, Jeff…

Providence Health & Services and Institute for Systems Biology affiliate to catalyze scientific wellness

Dr. Leroy Hood to serve as chief science officer for Providence FOR IMMEDIATE RELEASE SEATTLE – March 14, 2016 – With the goal of bringing personalized medicine to every patient, Providence Health & Services and the Institute for Systems Biology announced today an affiliation that will transform health care to a proactive mode that is focused on keeping patients well and identifying the earliest opportunities to reverse or even prevent…

Genetic Disease Breakthrough Published in ‘Nature Communications’

FOR IMMEDIATE RELEASE Genetic Disease Breakthrough Published in Nature Communications SEATTLE, DEC. 18, 2015 – A team of investigators based in Seattle, Amsterdam, and Luxembourg, have established the cause of a rare syndrome consistent with Fanconi Anemia, a chromosome instability disorder which is clinically typified by birth defects, bone marrow failure, leukemia, and susceptibility to solid tumors. The results were reported by researchers from the Institute for Systems Biology (Seattle),…

WRF Gifts $2M to ISB to Advance P4 Medicine

PRESS RELEASE from Washington Research Foundation: Sept. 30, 2015, Seattle –– Washington Research Foundation (WRF), which supports groundbreaking technology in the life sciences, physical sciences and information sciences in Washington State, announced today that it will provide the Institute for Systems Biology (ISB) with $2 million in funding to bring increased research power to Seattle, and help place this community at the center of the coming transformation of the health…

INTEGRATED VARIANTS FROM 13,000 COMPLETE GENOMES AVAILABLE TO PUBLIC IN KAVIAR DATABASE

FOR IMMEDIATE RELEASE SEATTLE, WA and FALLS CHURCH, VA, Sept. 23, 2015—The Institute for Systems Biology (ISB) and the Inova Translational Medicine Institute (ITMI) announced today a new release of Kaviar, the most comprehensive collection of human genomic variants currently available to the public. This release expands on the January 2015 release most notably by the addition of 3842 whole genome sequences provided by ITMI. Inova, a not-for-profit healthcare system…

New $500K OSPI Award Aids ISB’s Work with Marysville School District

Above: Dr. Dana Riley Black, Director for ISB’s Logan Center for Education, speaks to educators about how her team and other ISB researchers work with school districts. FOR IMMEDIATE RELEASE Marysville School District Scores $500,000 OSPI Funding for Science & Engineering Workshops for Teachers 3-Year Award Supports Partnership with ISB & UW Engineering to Provide Professional Development for District SEATTLE, May 1, 2015 – The Office of Superintendent of Public…

ISB Launches 3-Year Wilke Lyme Disease Project with $2.13M Funding

Study Utilizes Systems Approaches to Develop Diagnostics and Deeper Understanding of Chronic Lyme PRESS RELEASE, SEATTLE, March 26, 2015 – Institute for Systems Biology (ISB) has received $2.13 million in transformational gifts from Jeff and Liesl Wilke; Jeff and MacKenzie Bezos; and the Bay Area Lyme Foundation to tackle chronic Lyme disease, a highly complex and often misdiagnosed disease that can be debilitating for those who do not respond to…

ISB Taps Kathy Scanlan as New Chief Operating Officer

ISB announces the appointment of Kathy Scanlan as chief operating officer. Scanlan’s leadership career has spanned government, nonprofits and sports, and includes serving as the Executive Vice-President of the 1990 Seattle Goodwill Games Organizing Committee and as President of USA Gymnastics. Through Scanlan Consulting, her assignments have included working closely with the Washington State Legislature on ferry and transportation issues; strategic and business planning for museums, park facilities, and global health/discovery science…

ISB Awarded $6.5 Million NIH Contract to Develop ‘Cancer Genomics Cloud’ with Google and SRA International

PRESS RELEASE Institute for Systems Biology (ISB) has received a $6.5 million, up to two­-year, federally funded contract from the National Cancer Institute (NCI), National Institutes of Health (NIH). ISB is one of three organizations awarded a contract by NCI to develop a cloud-­based platform that will serve as a large­-scale data repository and provide the computational infrastructure necessary to carry out cancer genomics research at unprecedented scales. ISB’s Shmulevich…

ISB Gets $2.3 million NIH Grant to Use Single-Cell Technology to Fight Cancer

Pictured above: Dr. Qiang Tian, left, and Dr. Edward Lin, right, discuss single-cell analysis technologies developed at Institute for Systems Biology in Seattle. September 22, 2014 – ISB has received a $2.3 million NIH grant over four years in response to NCI’s “Provocative Questions” Initiative. The project will apply ISB’s most advanced single-cell omics technologies to an innovative clinical trial for colorectal cancer (ADAPT). Principal investigator Qiang Tian, MD, PhD,…

NIH awards $10.9 million to National Center for Dynamic Interactome Research

New $10.9 Million Grant from NIH

The NIH's National Institute of General Medical Sciences has issued a Biotechnology Resource Grant of $10.9 million over five years to the National Center for Dynamic Interactome Research (ncdir.org) project. This project is a collaboration among The Rockefeller University, Institute for Systems Biology, Seattle BioMed, University of California at San Francisco, New York University and New York Structural Biology Center. Michael Rout, of The Rockefeller University, is the Program Director/Principal…