ISB News

ISB researchers

Unveiling the Guerrilla Warfare Tactics of Mycobacterium Tuberculosis

ISB researchers have unveiled new insights on how Mycobacterium tuberculosis, the pathogen that causes tuberculosis, enters and exits a dormant state in human hosts. About a quarter of the world’s population has latent TB, so these important findings will enable and accelerate the discovery of more effective TB drugs.

ISB’s Dr. Nathan Price Inducted into AIMBE’s College of Fellows 

Dr. Nathan Price has been inducted into the American Institute for Medical and Biological Engineering’s (AIMBE) College of Fellows. Price was nominated, reviewed, and elected by peers and members of the College of Fellows for his contributions deriving medical and biological insights from large-scale data analysis and network modeling, and translating those insights to society.

Illustration of a person using a katana to slash a coronavirus in half

Merck, ISB, Swedish Collaborate In Trial to Understand, Treat COVID-19

ISB and Swedish Medical Center launched a study to follow hundreds of patients who contract COVID-19 to learn why those infected have drastically different outcomes. “Each of the COVID-19 patients has a unique lesson to teach us about how the medical and scientific community can respond most effectively to this pandemic,” said ISB President Dr. Jim Heath, who co-leads the study.

Education resources

During Coronavirus Outbreak, Free Online Resources for Stuck-At-Home K-12 Students

ISB Education is continually working to identify effective resources to support student learning. In response to the coronavirus outbreak and the closure of K-12 schools across the nation, we recognize that many schools and families are looking for resources to meet the needs of students.

CDC Coronavirus Image

ISB Statement Concerning the Ongoing Coronavirus Outbreak

ISB is committed to the health and safety of our research and administrative staff. Some of our scientists are conducting important COVID-19 research. Otherwise, ISB is adhering to Governor Jay Inslee’s stay-at-home orders. For the latest coronavirus information, please monitor the Centers for Disease Control and Prevention (CDC) webpage linked from this news item.

soldier

ISB Researchers Seek a Better Way to Identify Chronic Mild Traumatic Brain Injury

Mild traumatic brain injury (mTBI) has been a frequent injury among U.S. combatants, and blast-related mTBI has been called the “signature injury” from military conflicts in Iraq and Afghanistan. ISB researchers are working to develop new methods to identify molecular changes in the blood of war veterans diagnosed with chronic mTBI.

Dr. Christian Diener, postdoc in ISB's Gibbons Lab.

New Modeling Tool Allows Microbiome Researchers to Map Community Ecology to Ecosystem Function

A promising new open-source metabolic modeling tool provides microbiome researchers a path forward in predicting ecosystem function from community structure. News of the software package, called MICOM, was developed in part by researchers in ISB’s Gibbons Lab, and its uses were published in the journal mSystems.

Using Blood to Predict Gut Microbiome Diversity

Predicting the alpha diversity of an individual’s gut microbiome is possible by examining metabolites in the blood. The robust relationship between host metabolome and gut microbiome diversity opens the door for a fast, cheap and reliable blood test to identify individuals with low gut diversity.

Dr. Mary Kay Ross

ISB, BHRI Collaborate to Better Understand Significant Brain Impairment

ISB has entered into a scientific partnership with the Brain Health & Research Institute (BHRI), which opens its doors on September 3 in Seattle. BHRI was created by brain health expert Dr. Mary Kay Ross, and is dedicated to the evaluation, prevention, and treatment of neurodegenerative diseases, including Alzheimer’s Disease and dementia.

The Cancer Paradox

ISB’s Dr. Sui Huang uses the theory of complex systems and applies it to cancer research. In this video Q&A, he discusses the cancer paradox and highlights the importance of understanding the mechanism of what cancer treatments can backfire in order to open a new avenue for therapy and treatments.

The Science of Pregnancy

Pregnancy is a biological necessity for survival. Traditionally, however, our knowledge about pregnancy and pregnant women have lagged. Dr. Alison Paquette, a research scientist in ISB’s Hood-Price Lab, hosted a video question-and-answer session where she discussed pregnancy, the placenta, preterm birth, and much more.

Nathan Price

Dr. Nathan Price Named NAM Emerging Leader in Health and Medicine Scholar

The National Academy of Medicine (NAM) announced ISB’s Dr. Nathan Price as a 2019 Emerging Leader in Health and Medicine Scholar. NAM’s Emerging Leaders in Health and Medicine Program provides a platform for a new generation of leaders to collaborate with the NAM and its members across generations and fields of expertise.

Brain health expert Dr. Mary Kay Ross

Brain Health & Research Institute Enters Scientific Partnership with ISB

Brain health expert Dr. Mary Kay Ross announced the creation of the Brain Health & Research Institute (BHRI) in Seattle, and a scientific collaboration with ISB. Through that partnership, BHRI will blend the practical application of medical therapies and treatment protocols with ten advanced scientific analysis now available through personalized medicine and computational biology.

Town Hall Seattle panel

Expert Panel Discusses 21st Century Health at Town Hall Seattle Event

In a public panel discussion put on by Town Hall Seattle and ISB, legendary biologist Dr. Lee Hood, PSJH Chief Clinical Officer Dr. Amy Compton-Phillips, and PATH’s Program Leader of Diagnostics Tala de los Santos addressed the promise — and challenges — of implementing and practicing 21st century health care.

Qiang Tian, MD, PhD

ISB’s Dr. Qiang Tian Joins Shanghai’s National Research Center for Translational Medicine

In the two decades since joining Dr. Lee Hood as a postdoc, Dr. Qiang Tian has made a tremendous impact on ISB’s science and culture. March 31 is his final day at ISB, as he is returning to China and joining Shanghai’s National Research Center for Translational Medicine.

Biology students

Biology Classes ‘Come Alive’ After Teacher’s Summer with ISB

Kyle Kinzler, a high school biology teacher from Portland, Oregon, spent part of last summer at Institute for Systems Biology to evolve his curriculum and learn new ways to teach relevant, compelling and innovative content to his students. As a result, he says his classes has “come alive.”

Dr. Sean Gibbons

All About the Human Microbiome

The human microbiome is a relatively new area of research, and there are numerous questions surrounding it. What is the human microbiome? Can we change it? Does it make us sick? Keep us well? ISB Assistant Professor and microbiome researcher Dr. Sean Gibbons answers these questions — and many more.

Andrea Varela-Stokes

ISB’s Moritz Lab Lands NIH Grant to Study Lyme Disease

ISB’s Moritz Lab has received research funding totaling nearly $525,000 from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to develop “novel peptide based biomarkers for Lyme disease diagnostics.”