The Kane Lab, led by Dr. Alice Kane, is interested in identifying biological determinants of frailty in order to understand more about the molecular underpinnings of frailty and aging, to develop predictive biomarkers of frailty, and to identify targets to delay or prevent frailty.
Dr. Alice Kane at a glass whiteboard with her lab at ISB. Photo credit: Trevor Dykstra
Women are more frail – with attendant health problems – than men at every age but have a lower risk of mortality. To transform how we understand disease and health in aging for all older adults, Ling/Obrzut Assistant Professor Alice Kane’s research, supported by a prestigious new faculty NIH grant, aims to understand frailty and aging at the molecular level.
Dr. Alice Kane with her lab member Judy Wu at ISB. Photo credit: Trevor Dykstra
Age is the greatest cancer risk factor and plays a role in cancer progression, prognosis, and treatment. Why is not clear. The Kane Lab, with the Heath and Wei labs, is analyzing the aging tumor microenvironment – the interacting cells surrounding a tumor – to determine how it contributes to tumor development and treatment response in older people.
ISB hosted the Systems Biology of Aging Virtual Workshop in May 2024 for graduate students, postdocs, principal investigators, industry scientists, and educators. The course provided practical tools for performing multi-omic systems biology analyses to advance the study of aging.
ISB is excited to announce the arrival of our newest faculty member, Ling/Obrzut Assistant Professor Dr. Alice Kane. The Kane Lab will investigate the biological determinants of frailty in both males and females. In this Q&A, she discusses her research to date, her areas of interest, and much more.
Ling/Obrzut Assistant Professor
ISB