In March 2024, in special recognition of distinguished service to the Institute for Systems Biology, the Board of Directors appointed Dave Sabey as ISB’s first lifetime Director Emeritus. Dave’s 14-tenure on the ISB Board included service as Chair (2013-2019) and Chair Emeritus (2019-2024). Dave made a transformative contribution to ISB when he recognized that ISB and Providence would benefit from an affiliation, and then shepherded the affiliation. These visionary efforts opened up new opportunities for ISB translational science, faculty recruitment, and joint ISB-Providence groundbreaking studies in wellness, genomics, cancer and infectious diseases.