Fluidized bed reactor

How Microbes Evolve to Spatially Divide and Conquer an Environment 

ISB researchers examined representative organisms of two classes of microbes whose interaction contributes to the conversion of more than 1 gigaton of carbon into methane every year. They found that gene mutations selected over a relatively short timeframe in the two microbes led to distinct functions.

How Microbes Evolve to Spatially Divide and Conquer an Environment 
How Microbes Evolve to Spatially Divide and Conquer an Environment 
gibbons and johnson

Timing is Everything: ISB Study Finds Link Between Bowel Movement Frequency and Overall Health

Everybody poops, but not every day. An ISB-led research team examined the clinical, lifestyle, and multi-omic data of more than 1,400 healthy adults. How often people poop, they found, can have a large influence on one’s physiology and health.

Timing is Everything: ISB Study Finds Link Between Bowel Movement Frequency and Overall Health
Timing is Everything: ISB Study Finds Link Between Bowel Movement Frequency and Overall Health
Wei Wei, PhD

Dr. Wei Wei Promoted to Associate Professor

Wei Wei, PhD – an accomplished cancer researcher with expertise in biotechnology and cancer systems biology – has been promoted to ISB associate professor. The Wei Lab focuses on understanding how cancer cells adapt to therapeutic treatment to foster therapy resistance by coordinating their internal molecular machinery and how these adaptive changes evolve within diverse tumors influenced by the tumor microenvironment. 

Dr. Wei Wei Promoted to Associate Professor
Dr. Wei Wei Promoted to Associate Professor
Drs. Nitin Baliga and James Park

How Glioblastoma Resists Treatment – and Ways to Prevent It

Glioblastoma is one of the deadliest and most aggressive forms of primary brain cancer in adults and is known for its ability to resist treatment and to recur. ISB researchers have made breakthrough discoveries in understanding the mechanisms behind acquired resistance, focusing on a rare and stubborn group of cells within tumors called glioma stem-like cells.

How Glioblastoma Resists Treatment – and Ways to Prevent It
How Glioblastoma Resists Treatment – and Ways to Prevent It
screenshot of video for Hack Your Health: An Evening with Anjali Nayar and Dr. Sean Gibbons

Hack Your Health: An Evening with Anjali Nayar and Dr. Sean Gibbons

Netflix's “Hack Your Health: The Secrets of Your Gut" is a documentary that merged gut microbiome experts, four individuals – including a well-known hot dog eating champion – facing personal battles with gastrointestinal health, and a unique, effective visual method of “showing” the gut microbiome in action. 

Hack Your Health: An Evening with Anjali Nayar and Dr. Sean Gibbons
Hack Your Health: An Evening with Anjali Nayar and Dr. Sean Gibbons
screenshot of video for A New Path Toward Microbiome-Informed Precision Nutrition

A New Path Toward Microbiome-Informed Precision Nutrition

ISB researchers have developed a novel way to simulate personalized, microbiome-mediated responses to diet. They use a microbial community-scale metabolic modeling (MCMM) approach to predict individual-specific short-chain fatty acid production rates in response to different dietary, prebiotic, and probiotic inputs.

A New Path Toward Microbiome-Informed Precision Nutrition
A New Path Toward Microbiome-Informed Precision Nutrition
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