ISB News

Baliga Lab: Uncovering the Genetic Adaptability of Tuberculosis

3 Bullets: The Institute for Systems Biology and Seattle BioMed have collaborated to reconstruct the gene regulatory network of the human pathogen Mycobacterium tuberculosis. Finely tuned gene regulation has allowed Mycobacterium tuberculosis to survive unnoticed in an apparently healthy host for decades; understanding those subtleties is critical for advancing treatment. The identification of co-regulated sets of genes and their regulatory influences offers validated predictions that will help guide future research…

Decoding the Microbial Gene-Recycling Program: Researchers 'Unzip' Genetic Instruction Manuals

New Open-Access Multiscale Model Captures Dynamic Molecular Processes in Unprecedented Detail

3 Bullets: Microbes are efficient because their streamlined genomes allow them to evolve and adapt rapidly to complex environmental changes. Decoding the highly-compressed information within a microbial genome requires sophisticated systems biology tools to map the genetic programs, and understand how they are executed. ISB researchers invented novel algorithms to unzip and decode microbial genomes into the EGRIN 2.0, an open-access multiscale model that captures instructions for executing the dynamic…

Now Accepting ISB Internship Applications

ISB’s summer internships for high school and undergraduate students are highly competitive — who wouldn’t want to work leading experts in systems biology research? The application process is now open. If you or someone you know may be interested in applying, visit the following links: High School Internships Undergraduate Internships

Science Education Impact

The educators who work at ISB continue to influence how science is taught in the State of Washington. Claudia Ludwig and Dina Kovarik, members of the Baliga Lab education team, recently helped the Highline School District apply for a $1,000 grant to use toward systems science materials and teacher training. Highline’s Arts and Academics Academy received the award, which will also provide students with “real-world” lab experience.

Open Science: A Hack Your PhD Interview with Dr. Nitin Baliga

Célya Gruson-Daniel, the founder of HackYourPhD, has been traveling across the United States to make a documentary about open science. She stopped by ISB on Aug. 5, 2013, to interview Dr. Nitin Baliga, who is our senior vice president and director. The short interview is below. Learn more about the Hack Your PhD documentary at this site: http://hackyourphd.org/USA