The Institute for Systems Biology, where science solves problems, saves lives, and benefits human life on a global scale. If that’s not beautiful, we don’t know what is.
A microbial community-scale metabolic model of an individual’s gut generated by MICOM data and the data visualization tool Gephi. Image credit: Gibbons Lab/ISB.
ISB is uncovering new solutions to the world’s most pressing health problems.
ISB Building at dusk in South Lake Union, Seattle. Photo credit: Trevor Dykstra.
ISB employs over 170 staff from 25 countries. We are committed to fostering gender equity and increasing the representation of individuals from communities historically underrepresented in STEM.
Members of the Kuchina Lab working at ISB in Seattle. Photo credit: Scott Eklund/Red Box Pictures.
The Institute for Systems Biology (ISB) is a nonprofit scientific research organization located in Seattle. We believe that science has the power to transform health. You have an opportunity to play an essential role in the future of human health. When you get involved, you enable our researchers to tackle some of the biggest challenges of our time. Together we can build a better, brighter, healthier future.
Cancer is complex and requires a sophisticated systems approach to understand and treat it. ISB researchers are pursuing several complex and cross-disciplinary means to better create more personalized therapeutics and simulate which treatments will be most effective.
Each of us has a microbiome — trillions of microorganisms that reside in and on our bodies. ISB researchers study the microbiome’s role in human health and translate this knowledge into approaches designed to promote better health for every individual.
Our infectious disease research addresses a wide range of global health initiatives. We are exploring new approaches that focus on cutting-edge treatments and preventive measures to fight infectious diseases.
Read the latest news of our transformational research, devoted scientists and educators, recent and upcoming events, and much more.
In the December installment of the 2024-25 academic year roundup, we detail lab kits ISB Education sent out to schools across the nation, uplifting quotes from teachers who worked with ISB Education this fall, and additions to the LASER Leadership Team.
Reflecting on the past year, ISB has a lot to celebrate: groundbreaking research published in leading scientific journals, well-earned promotions, widespread media coverage, and more. Enjoy our year-in-review roundup highlighting some of the important, interesting, and impactful highlights of 2024.
ISB has been selected as a winner of the 2024 Amazon Web Services (AWS) IMAGINE Grant. The grant will support ISB’s continued development of My Digital Gut, an online decision-support platform that will help make microbiome-informed nutrition and healthcare personalized, predictive, and preventive.
President and Professor Jim Heath is dedicated to advancing precision medicine from benchtop to bedside, particularly in oncology. His research addresses fundamental scientific bottlenecks that can unlock solutions to broader challenges.
Professor Wei Wei’s research focuses on molecular and cellular analysis within systems biomedicine. The Wei Lab aims to tackle critical questions and foster new insights in fundamental and translational cancer research.
ISB Assistant Professor Anna Kuchina studies bacteria at the single-cell level, using advanced technologies to understand how bacteria behave in complex settings such as biofilms living in the human body.