Mario Arrieta-Ortiz, PhD

Dr. Arrieta-Ortiz builds genome-wide models to uncover regulatory and metabolic programs that coordinate physiological changes that allow bacteria to thrive in the host environment and survive antibiotic-induced stress. His goal is to identify pathogen vulnerabilities to inform the design of new antimicrobial therapies.

During his PhD at New York University, Dr. Arrieta-Ortiz developed and applied computational tools to construct accurate and informative gene regulatory network models that integrate transcriptional and post-transcriptional regulation. At ISB, Dr. Arrieta-Ortiz is developing conceptual and systems biology frameworks to dissect microbial adaptive strategies. Dr. Arrieta-Ortiz has applied these integrative frameworks to characterize in vivo virulence and adaptive responses of multiple bacterial pathogens, including Clostridioides difficile and Mycobacterium tuberculosis.

PhD, Biology, New York University

Computational Biology, Network Biology, Antimicrobial Resistance, Host-pathogen interactions