Dr. Hadlock’s research aim is to understand transitions between wellness and disease, and accelerate translational research by integrating clinical data into systems biology at scale. Her long-term vision is to improve the lives of people with immune-mediated inflammatory diseases (IMIDs), which include ulcerative colitis, Crohn’s disease, rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis, multiple sclerosis, systemic lupus erythematosus, Sjögren’s syndrome and others, including numerous rare diseases.

The Hadlock Lab focuses on developing models from high-fidelity, longitudinal observations of multiomics, phenotype, exposures and patient-centered outcomes. Current areas of research include IMIDs, immunomodulatory medications, chronic multimorbidities and maternal/fetal health, as well as improving machine learning methods and knowledge graphs for supporting translational systems medicine.

She received her MD at the University of Washington School of Medicine in 2015, including training in the Rural/Urban Underserved Pathway. Prior to that, she was a Principal Software Engineer in research and development at Microsoft, analyzing and optimizing end-user quality for natural language processing, geographic information systems and real-time digital imaging. She successfully led numerous teams working on technologies that have been used by hundreds of millions of people worldwide.