Publications

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2025

Alcindor, Thierry, James Tankel, Pierre-Olivier Fiset, Sanjima Pal, Touhid Opu, Michael Strasser, Mehrnoush Dehghani, et al. 2025. “Phase 2 Trial of Perioperative Chemo-Immunotherapy for Gastro-Esophageal Adenocarcinoma: The Role of M2 Macrophage Landscape in Predicting Response.” Cell Reports. Medicine 6 (4): 102045. http://doi.org/10.1016/j.xcrm.2025.102045. Cite
Alipour, Ehsan, Samuel Gratzl, Ahmad Algohary, Hao Lin, Manoj Bapat, Duy Do, Charlotte Baker, et al. 2025. “Multimodal Deep Learning Model to Estimate CT-Based Body Composition Measures Using Chest Radiographs and Clinical Data.” medRxiv. http://doi.org/10.1101/2025.01.16.25320684. Cite Download
Arias-Gaguancela, Omar, Carmen Palii, Mehar Un Nissa, Marjorie Brand, and Jeff Ranish. 2025. “QuickProt: A Bioinformatics and Visualization Tool for DIA and PRM Mass Spectrometry-Based Proteomics Datasets.” bioRxiv: The Preprint Server for Biology, 2025.03.24.645047. http://doi.org/10.1101/2025.03.24.645047. Cite
Armstrong, Sujit Silas, Daniel G. Chen, Sunil Kumar, James R. Heath, Matthew J. Feinstein, John R. Greenland, Daniel R. Calabrese, Lewis L. Lanier, Klaus Ley, and Avishai Shemesh. 2025. “CITE-Seq Analysis Reveals a Differential Natural Killer Cell SPON2 Expression in Cardiovascular Disease Patients Impacted by Human-Cytomegalovirus Serostatus and Diabetes.” International Journal of Molecular Sciences 26 (3): 1369. http://doi.org/10.3390/ijms26031369. Cite Download
Baliga, Nitin, Kathryn Stankiewicz, Jacob Valenzuela, Serdar Turkarslan, Wei-Ju Wu, Kelly Gomez-Campo, Nicolas Locatelli, et al. 2025. “Alternative Splicing in a Coral during Heat Stress Acclimation and Recovery.” Research Square. http://doi.org/10.21203/rs.3.rs-6025431/v1. Cite Download
Baumgartner, Andrew, Max Robinson, Nilufer Ertekin-Taner, Todd E. Golde, Suman Jaydev, Sui Huang, Jennifer Hadlock, and Cory Funk. 2025. “Fokker-Planck Diffusion Maps of Microglial Transcriptomes Reveal Radial Differentiation into Substates Associated with Alzheimer’s Pathology.” Communications Biology 8 (1): 279. http://doi.org/10.1038/s42003-025-07594-y. Cite
Berndt, Jason D., Fergal J. Duffy, Mark D. D’Ascenzo, Leslie R. Miller, Yijun Qi, G. Adam Whitney, Samuel A. Danziger, et al. 2025. “A Multivariate Cell-Based Liquid Biopsy for Lung Nodule Risk Stratification: Analytical Validation and Early Clinical Evaluation.” The Journal of Liquid Biopsy 9: 100313. http://doi.org/10.1016/j.jlb.2025.100313. Cite
Bhinder, Bhavneet, Verena Friedl, Sunantha Sethuraman, Davide Risso, Kami E. Chiotti, R. Jay Mashl, Kyle P. Ellrott, et al. 2025. “Pan-Cancer Immune and Stromal Deconvolution Predicts Clinical Outcomes and Mutation Profiles.” Scientific Reports 15 (1): 23921. http://doi.org/10.1038/s41598-025-09075-y. Cite
Caminero, Alberto, Carolina Tropini, Mireia Valles-Colomer, Dennis L. Shung, Sean M. Gibbons, Michael G. Surette, Harry Sokol, et al. 2025. “Credible Inferences in Microbiome Research: Ensuring Rigour, Reproducibility and Relevance in the Era of AI.” Nature Reviews. Gastroenterology & Hepatology. http://doi.org/10.1038/s41575-025-01100-9. Cite
Carr, Alex V., Anne E. Otwell, Kristopher A. Hunt, Yan Chen, James Wilson, José P. Faria, Filipe Liu, et al. 2025. “Emergence and Disruption of Cooperativity in a Denitrifying Microbial Community.” The ISME Journal 19 (1): wraf093. http://doi.org/10.1093/ismejo/wraf093. Cite
Carr, Alex V., Nitin S. Baliga, Christian Diener, and Sean M. Gibbons. 2025. “Personalized Clostridioides Difficile Colonization Risk Prediction and Probiotic Therapy Assessment in the Human Gut.” Cell Systems, 101367. http://doi.org/10.1016/j.cels.2025.101367. Cite
Cavon, Jacob, Melissa Basso, Kathrin Cohen Kadosh, and Sean M Gibbons. 2025. “The Human Gut Microbiome and Sleep across Adulthood: Associations and Therapeutic Potential.” Letters in Applied Microbiology, ovaf043. http://doi.org/10.1093/lambio/ovaf043. Cite Download
Chambwe, Nyasha, Scott R. Kennedy, Brendan F. Kohrn, Pavlo Lazarchuk, Mario Leutert, Guangrong Qin, Bahar Tercan, et al. 2025. “Cellular Heterogeneity and Therapeutic Response Profiling of Human IDH+ Glioma Stem Cell Cultures.” bioRxiv: The Preprint Server for Biology, 2025.07.29.667532. http://doi.org/10.1101/2025.07.29.667532. Cite
Contreras-Moreira, Bruno, Eshan Sharma, Shradha Saraf, Guy Naamati, Parul Gupta, Justin Elser, Dmytro Chebotarov, et al. 2025. “A Pan-Gene Catalogue of Asian Cultivated Rice.” bioRxiv. http://doi.org/10.1101/2025.02.17.638606. Cite Download
Dacon, Cherrelle, Re’em Moskovitz, Kristian Swearingen, Lais Da Silva Pereira, Yevel Flores-Garcia, Maya Aleshnick, Sachie Kanatani, et al. 2025. “Protective Antibodies Target Cryptic Epitope Unmasked by Cleavage of Malaria Sporozoite Protein.” Science (New York, N.Y.) 387 (6729): eadr0510. http://doi.org/10.1126/science.adr0510. Cite
Bruijn, Ino de, Milen Nikolov, Clarisse Lau, Ashley Clayton, David L. Gibbs, Elvira Mitraka, Dar’ya Pozhidayeva, et al. 2025. “Sharing Data from the Human Tumor Atlas Network through Standards, Infrastructure and Community Engagement.” Nature Methods 22 (4): 664–71. http://doi.org/10.1038/s41592-025-02643-0. Cite
Deutsch, Eric W., Luis Mendoza, and Robert L. Moritz. 2025. “Quetzal: Comprehensive Peptide Fragmentation Annotation and Visualization.” Journal of Proteome Research. http://doi.org/10.1021/acs.jproteome.5c00092. Cite
Diener, Christian, Hannah D. Holscher, Klara Filek, Karen D. Corbin, Christine Moissl-Eichinger, and Sean M. Gibbons. 2025. “Metagenomic Estimation of Dietary Intake from Human Stool.” Nature Metabolism. http://doi.org/10.1038/s42255-025-01220-1. Cite Download
Dirvin, Brooke, Heeju Noh, Lorenzo Tomassoni, Danting Cao, Yizhuo Zhou, Xiangyi Ke, Jun Qian, et al. 2025. “Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium.” Science Advances 11 (20): eadu2079. http://doi.org/10.1126/sciadv.adu2079. Cite
Ellis, Dylan, Kengo Watanabe, Tomasz Wilmanski, Michael S. Lustgarten, Andres V. Ardisson Korat, Gwênlyn Glusman, Jennifer Hadlock, et al. 2025. “APOE Genotype and Biological Age Impact Inter-Omic Associations Related to Bioenergetics.” Aging 17 (5): 1105–38. http://doi.org/10.18632/aging.206243. Cite Download
Ellrott, Kyle, Christopher K. Wong, Christina Yau, Mauro A. A. Castro, Jordan A. Lee, Brian J. Karlberg, Jasleen K. Grewal, et al. 2025. “Classification of Non-TCGA Cancer Samples to TCGA Molecular Subtypes Using Compact Feature Sets.” Cancer Cell. http://doi.org/10.1016/j.ccell.2024.12.002. Cite
Fain, Mindy J., Benjamin D. Horne, Leora I. Horwitz, Tanayott Thaweethai, Meredith Greene, Mady Hornig, Ariela R. Orkaby, et al. 2025. “Age-Related Changes in the Clinical Picture of Long COVID.” Journal of the American Geriatrics Society n/a (n/a). http://doi.org/10.1111/jgs.70043. Cite
Fecho, Karamarie, Gwênlyn Glusman, Sergio E. Baranzini, Chris Bizon, Matthew Brush, William Byrd, Lawrence Chung, et al. 2025. “Announcing the Biomedical Data Translator: Initial Public Release.” Clinical and Translational Science 18 (7): e70284. http://doi.org/10.1111/cts.70284. Cite
Flower, Cameron T., Chunmei Liu, Hui-Yu Chuang, Xiaoyang Ye, Hanjun Cheng, James R. Heath, Wei Wei, and Forest M. White. 2025. “Signaling and Transcriptional Dynamics Underlying Early Adaptation to Oncogenic BRAF Inhibition.” Cell Systems, 101239. http://doi.org/10.1016/j.cels.2025.101239. Cite
Freidin, Maxim B., and Jared C. Roach. 2025. “Editorial: A Year in Review: Discussions in Human and Medical Genomics.” Frontiers in Genetics 16: 1618183. http://doi.org/10.3389/fgene.2025.1618183. Cite
Gao, Huanyao, Kate Jensen, Jarred Nesbitt, Mark Ostroot, Gregory A. Cary, Jesse Wiley, Sergey Trushin, et al. 2025. “Mitochondrial Complex I Deficiency Induces Alzheimer’s Disease-like Signatures That Are Reversible by Targeted Therapy.” Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 21 (8): e70519. http://doi.org/10.1002/alz.70519. Cite
Geng, Linda N., Kristine M. Erlandson, Mady Hornig, Rebecca Letts, Caitlin Selvaggi, Hassan Ashktorab, Ornina Atieh, et al. 2025. “2024 Update of the RECOVER-Adult Long COVID Research Index.” JAMA. http://doi.org/10.1001/jama.2024.24184. Cite
Gilbert, Jack A., Meghan B. Azad, Fredrik Bäckhed, Martin J. Blaser, Mariana Byndloss, Charles Y. Chiu, Hiutung Chu, et al. 2025. “Clinical Translation of Microbiome Research.” Nature Medicine, 1–15. http://doi.org/10.1038/s41591-025-03615-9. Cite
Glen, Amy K., Eric W. Deutsch, and Stephen A. Ramsey. 2025. “PloverDB: A High-Performance Platform for Serving Biomedical Knowledge Graphs as Standards-Compliant Web APIs.” bioRxiv: The Preprint Server for Biology, 2025.03.09.642156. http://doi.org/10.1101/2025.03.09.642156. Cite
Glen, Amy K., Eric W. Deutsch, and Stephen A. Ramsey. 2025. “PloverDB: A High-Performance Platform for Serving Biomedical Knowledge Graphs as Standards-Compliant Web APIs.” Bioinformatics (Oxford, England) 41 (7): btaf380. http://doi.org/10.1093/bioinformatics/btaf380. Cite
Godsil, Marshall, Nathaniel L. Ritz, Siddarth Venkatesh, and Alexander J. Meeske. 2025. “Gut Phages and Their Interactions with Bacterial and Mammalian Hosts.” Journal of Bacteriology, e0042824. http://doi.org/10.1128/jb.00428-24. Cite
Gomez-Artiguez, Leticia, Samuel de la Cámara-Fuentes, Zhi Sun, María Luisa Hernáez, Ana Borrajo, Aída Pitarch, Gloria Molero, et al. 2025. “Candida Albicans: A Comprehensive View of the Proteome.” Journal of Proteome Research 24 (4): 1636–48. http://doi.org/10.1021/acs.jproteome.4c01020. Cite Download
Grewal, Jasleen K., A. Gordon Robertson, Kyle Ellrott, Christopher K. Wong, Jordan A. Lee, Christina Yau, Bahar Tercan, et al. 2025. “Protocol for Obtaining Cancer Type and Subtype Predictions Using subSCOPE.” STAR Protocols 6 (2): 103705. http://doi.org/10.1016/j.xpro.2025.103705. Cite
Gupta, Anika, Norma Morella, Dmitry Sutormin, Naisi Li, Karl Gaisser, Alexander Robertson, Yaroslav Ispolatov, Georg Seelig, Neelendu Dey, and Anna Kuchina. 2025. “Combinatorial Phenotypic Landscape Enables Bacterial Resistance to Phage Infection.” bioRxiv. http://doi.org/10.1101/2025.01.13.632860. Cite Download
Gupta, Vishal K., Vijaya V. Vaishnavi, Mario L. Arrieta-Ortiz, Abhirami P.s., Jyothsna K.m., Sharumathi Jeyasankar, Varun Raghunathan, Nitin S. Baliga, and Rachit Agarwal. 2025. “3D Hydrogel Culture System Recapitulates Key Tuberculosis Phenotypes and Demonstrates Pyrazinamide Efficacy.” Advanced Healthcare Materials n/a (n/a): 2304299. http://doi.org/10.1002/adhm.202304299. Cite
Gupta, Priya, Nastaran Rezakhani, Lucia Pazzagli, Hardik Patel, Gigliola Zanghi, Mohd Kamil, Alexander Watson, et al. 2025. “Glycosylation of Plasmodium Falciparum TRAP Is Essential for Infection of Mosquito Salivary Glands.” bioRxiv: The Preprint Server for Biology, 2025.06.26.658380. http://doi.org/10.1101/2025.06.26.658380. Cite
Hatzakis, Kiara, Zachary MacMillen, Payton Kirtley, Maya Aleshnick, Thomas Martinson, Priya Gupta, Kristian E. Swearingen, Brandon K. Wilder, James W. Davie, and Marion Avril. 2025. “A 3D Culture Model Facilitates Mass Production of in Vitro Plasmodium Falciparum Haemolymph-like Sporozoites.” Malaria Journal 24 (1): 224. http://doi.org/10.1186/s12936-025-05471-x. Cite
Heath, James R., and RECOVERY Collaborative Group. 2025. “Higher Dose Corticosteroids in Patients Admitted to Hospital with COVID-19 Who Are Hypoxic but Not Requiring Ventilatory Support (RECOVERY): A Randomised, Controlled, Open-Label, Platform Trial.” Lancet (London, England) 401 (10387): 1499–1507. http://doi.org/10.1016/S0140-6736(23)00510-X. Cite Download
Hodges, Frank M., Sundareswar Pullela, Guy Cohen, Akshay Mulgund, Jared C. Roach, and Stephen A. Ramsey. 2025. “Using AI to Improve Diagnosis and Treatment of Rare Diseases: A Chat Agent for Equitable and Accessible Healthcare.” In Artificial Intelligence in Medicine, edited by Riccardo Bellazzi, José Manuel Juarez Herrero, Lucia Sacchi, and Blaž Zupan, 186–91. Cham: Springer Nature Switzerland. http://doi.org/10.1007/978-3-031-95841-0_35. Cite
Huang, Sui, Ana M. Soto, and Carlos Sonnenschein. 2025. “The End of the Genetic Paradigm of Cancer.” PLOS Biology 23 (3): e3003052. http://doi.org/10.1371/journal.pbio.3003052. Cite Download
Hwang, Yeon-Mi, Jennifer M. Hah, Jennifer E. Bramen, Jennifer J. Hadlock, and Tina Hernandez-Boussard. 2025. “Short-Term Mortality after Opioid Initiation among Opioid-Naïve and Non-Naïve Patients with Dementia: A Retrospective Cohort Study.” BMC Medicine 23 (1): 340. http://doi.org/10.1186/s12916-025-04172-1. Cite Download
Jatt, Lauren P, Kevin M Gillespie, Phuong Van, Stephen L Hoffman, Lisa A Jackson, Sean C Murphy, James R Heath, and James G Kublin. 2025. “Manuscript Title: Cytokines Associated With Moderate and Severe Adverse Events During a Sporozoite Malaria Vaccine Trial with Controlled Human Malaria Infection.” The Journal of Infectious Diseases, jiaf435. http://doi.org/10.1093/infdis/jiaf435. Cite
Jiang, Boyu, Nick Quinn-Bohmann, Christian Diener, Vignesh Bose Nathan, Yu Han-Hallett, Lavanya Reddivari, Sean M. Gibbons, and Priyanka Baloni. 2025. “Understanding Disease-Associated Metabolic Changes in Human Colonic Epithelial Cells Using the iColonEpithelium Metabolic Reconstruction.” PLoS Computational Biology 21 (7): e1013253. http://doi.org/10.1371/journal.pcbi.1013253. Cite
Kalyuzhnyy, Anton, Patrick A. Eyers, Claire E. Eyers, Eric W. Deutsch, and Andrew R. Jones. 2025. “Applying a Conservation-Based Approach for Predicting Novel Phosphorylation Sites in Eukaryotes and Evaluating Their Functional Relevance.” bioRxiv. http://doi.org/10.1101/2025.01.09.632054. Cite Download
Kalyuzhnyy, Anton, Patrick A. Eyers, Claire E. Eyers, Eric W. Deutsch, and Andrew R. Jones. 2025. “Applying a Conservation-Based Approach for Predicting Novel Phosphorylation Sites in Eukaryotes and Evaluating Their Functional Relevance.” Journal of Proteome Research. http://doi.org/10.1021/acs.jproteome.5c00278. Cite
Li, Luna Xingyu, Boris Aguilar, John Gennari, and Guangrong Qin. 2025. “LM-Merger: A Workflow for Merging Logical Models with an Application to Gene Regulatory Network Models.” BMC Bioinformatics 26 (1): 178. http://doi.org/10.1186/s12859-025-06212-2. Cite
Lin, Meng-Lay, John W. Hickey, Adam Passman, Emanuela Carlotti, Shruthi Devkumar, Yannick H. Derwa, Joanne ChinAleong, et al. 2025. “Alterations of the Composition and Spatial Organization of the Microenvironment Following Non-Dysplastic Barrett’s Esophagus through Progression to Cancer.” bioRxiv: The Preprint Server for Biology, 2025.06.09.657642. http://doi.org/10.1101/2025.06.09.657642. Cite
Lucas Beckett, Isabelle A., Kate R. Emery, Josiah T. Wagner, Kathleen Jade, Benjamin A. Cosgrove, John Welle, J. B. Rinaldi, et al. 2025. “Geno4ME Study: Implementation of Whole Genome Sequencing for Population Screening in a Large Healthcare System.” Npj Genomic Medicine 10 (1): 50. http://doi.org/10.1038/s41525-025-00508-1. Cite Download
Mardinoglu, Adil, Hasan Turkez, Minho Shong, Vishnuvardhan Pogunulu Srinivasulu, Jens Nielsen, Bernhard O Palsson, Leroy Hood, and Mathias Uhlen. 2025. “Longitudinal Big Biological Data in the AI Era.” Molecular Systems Biology, 1–19. http://doi.org/10.1038/s44320-025-00134-0. Cite
Mukherjee, Ishita, James H. Park, Anoop P. Patel, and Nitin S. Baliga. 2025. “Transcriptional Mechanisms of Phenotypic Plasticity in Glioblastoma.” Journal of Clinical Oncology 42 (16_suppl): e14027–e14027. http://doi.org/10.1200/JCO.2024.42.16_suppl.e14027. Cite