Ulrike Kusebauch, PhD

Dr. Kusebauch’s research activities include the development and application of proteomic technologies, with a particular focus on targeted proteomics in biomedical research. Dr. Kusebauch studied Pharmaceutical Chemistry and obtained her Ph.D. in Biochemistry at the Max Planck Institute of Biochemistry (Germany) focusing on peptide/organic chemistry and conformational studies at temporal resolution. For her postdoctoral work, she joined the group of Prof. Ruedi Aebersold where she contributed to the development of targeted proteomics by selected reaction monitoring (SRM).

Dr. Kusebauch continued her research at ISB where she developed complete proteome SRM and SWATH mass spectrometry resources for human and other organisms, e.g., the Human SRMAtlas (www.srmatlas.org), a public available resource of targeted assays to quantify any protein in the human proteome, and applies quantitative technologies to spatial and temporal proteome dynamics and biochemical mechanisms in infectious and chronic human diseases. Other work includes the discovery of tyrosine phosphorylation in Mycobacterium tuberculosis revealing a previously unrecognized post-translational modification system in a human pathogen that claims ∼1.4 million lives every year. Dr. Kusebauch received the Human Proteome Organization Discovery in Proteomics Sciences Award 2018 that recognizes the outstanding efforts and achievements of individuals in the field of proteomics.

Proteomics, Mass Spectrometry, Post-translational Modification (PTM’s), Protein Biochemistry, Systems Biology, Peptide Chemistry, Pharmaceutical Chemistry