Location: Seattle (Hybrid or On-Site)

Join ISB as Chief Operating Officer

Bring your leadership, vision, and commitment to ISB. Help us transform the future of health through science.

ISB lab, female scientist at work

The Institute for Systems Biology (ISB), a world-renowned biomedical research institute located in Seattle’s vibrant South Lake Union neighborhood, is seeking a strategic, dynamic Chief Operating Officer (COO). This pivotal executive role partners directly with the President to drive institutional strategy and oversee key operational functions including Finance, HR, IT, Communications, Sponsored Projects, Facilities, Development, and Innovation.

If you’re a seasoned leader with a proven track record in strategic financial management, operational excellence, and organizational leadership — especially within complex, mission-driven environments — this is your opportunity to make a lasting impact on cutting-edge science and the future of human health.

View Job Description

Why Join ISB?

isb building

Exceptional Location

South Lake Union offers a unique blend of urban convenience and PNW natural beauty. Work just steps away from Lake Union’s waterfront trails, top-tier research hubs, and some of Seattle’s best restaurants and coffee.

people working in a lab

Leadership Opportunity

The COO provides strategic leadership across ISB’s operations, serving as the President’s key advisor and thought partner, and representing the institute to the Board of Directors, external partners, and internal community.

lab action

Generous Compensation & Benefits

We offer a competitive salary and a comprehensive benefits package. The expected annual pay range for the position is $226,000 – $325,000.

ISB brand icon

Apply Now

Bring your leadership, vision, and commitment to ISB. Help us transform the future of health through science.