ISB in collaboration with the NCI Cancer Systems Biology Consortium and MC2 Centers presents a free virtual workshop

Spatial Multi-Omics for Cancer Systems Biology

Monday, February 12 from 8:30 - 3 PST


Recordings Coming Soon

About the Workshop

ISB is hosting a free one-day Spatial Multi-Omics for Cancer Systems Biology virtual workshop. This virtual workshop will consist of four sessions on topics including: experimental methods, computational algorithms, applications of spatial multi-omics and a practical methods tutorial. The workshop will include the use of Jupyter notebooks and GitHub software to teach computational spatial multi-omics data analysis. The intended audience is graduate students, postdocs, principal investigators, industry scientists, and educators.

Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan

Workshop Organizers

Organized by the ST-Analytics Program within the NCI Cancer Systems Biology Consortium.

James R. Heath
Jim Heath, PhD
President and Professor, ISB
Rong Fan
Rong Fan, PhD
Professor, Yale University
Wei Wei
Wei Wei, PhD
Assistant Professor, ISB
Vésteinn Thorsson
Vésteinn Thorsson, PhD
Principal Scientist, ISB

 

Speakers

Session One: Experimental and Computational Methods I

James R. Heath
Session Chair: Jim Heath, PhD
President and Professor, ISB
Rong Fan
Rong Fan, PhD
Professor, Yale University
Ruben Dries
Ruben Dries, PhD
Assistant Professor, Medicine, Boston University
Lu Wei
Lu Wei, PhD
Assistant Professor of Chemistry, Caltech

Session Two: Experimental and Computational Methods II

Vésteinn Thorsson
Session Chair: Vésteinn Thorsson, PhD
Principal Scientist, ISB

Robert Krueger
Robert Krueger, PhD
Assistant Professor, Computer Science and Engineering, NYU
Joseph Beechem
Joseph Beechem, PhD
Chief Scientific Officer, NanoString
Lyla Atta
Lyla Atta
MD-PhD Candidate, Johns Hopkins University

 

Session Three: Applications of Spatial Multi-Omics

Wei Wei
Session Chair: Wei Wei, PhD
Assistant Professor, ISB
Katie Campbell
Katie Campbell, PhD
Adjunct Instructor, Medicine, UCLA
Sandro Santagata
Sandro Santagata, MD, PhD
Associate Professor, Harvard Medical School

 

Session Four: Practical Methods in Spatial Omics

Rong Fan
Session Chair: Rong Fan, PhD
Professor, Yale University
Shuozhen Bao
Shuozhen Bao
PhD Student, Yale University
Alev Baysoy
Alev Baysoy
PhD Student, Yale University
Zhiliang Bai
Zhiliang Bai, PhD
Postdoctoral Associate, Yale University

Agenda

8:30 a.m. - 3 p.m. PST.

Time Talk Info Slides
8:30 - 8:45 Session One: Experimental and Computational Methods I
Chair: Jim Heath, PhD
Introduction and goals of the workshop
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8:45 - 9:05 Speaker: Rong Fan, PhD
Sequencing-based spatial multi-omics mapping
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9:05 - 9:25 Speaker: Ruben Dries, PhD
The GIOTTO software tools
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9:25 - 9:45 Speaker: Lu Wei, PhD
Spatial metabolic imaging
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9:45 - 10:00 15-minute Q&A
All Speakers from Session One
Moderated by Session Chair
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10:00 - 10:15 Break
10:15 - 10:30 Session Two: Experimental and Computational Methods II
Chair: Vésteinn Thorsson, PhD
Introduction and relating spatial features across assay platforms
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10:30 - 10:50 Speaker: Robert Krueger, PhD
Visual analytics for imaging-based spatial biology profiling
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10:50 - 11:10 Speaker: Joseph Beechem, PhD
Spatial molecular imaging of FFPE cancer samples at any spatial-plex allows true systems biology understanding
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11:10 - 11:30 Speaker: Lyla Atta
Evaluating normalization approaches for imaging-based spatial profiling technologies
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11:30 - 11:45 15-minute Q&A
All Speakers from Session Two
Moderated by Session Chair
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11:45 - 12:00 Break
12:00 - 12:05 Session Three: Applications of Spatial Multi-Omics
Chair: Wei Wei, PhD
Introduction to applications of spatial multiomics
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12:05 - 12:25 Speaker: Katie Campbell, PhD
Applications of spatial multiomics tools
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12:25 - 12:45 Speaker: Sandro Santagata, MD, PhD
Applications of spatial multiomics tools
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12:45 - 13:00 15-minute Q&A
All Speakers from Session Three
Moderated by Session Chair
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13:00 - 13:15 Break
13:15 - 15:00 Session Four: Practical Methods in Spatial Omics
Chair: Rong Fan, PhD
Rong Fan and members of his group from Yale University (Shuozhen Bao, Alev Baysoy, Zhiliang Bai) lead a practical tutorial with Jupyter notebooks and GitHub software, to teach ‘hands-on’ experimental methods and computational tools for spatial omics and data analysis.
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GitHub Link

Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan
Image Courtesy Rong Fan