Cell Dynamics

Cell dynamics aims to understand biological complexity in the context of the modular organization of the cell. The three-dimensional structure of the cell gives biological systems the ability to sequester, tightly regulate, and increase the efficiency of many cellular systems.

However, this structure is not static. The organelles, specialized domains, and macromolecular machines inside the cell are extremely dynamic, responding both to the internal state of the cell and to external stimuli.

Systems biology with cell biology combine to help study the origins and dynamics of organelles to understand the networks that underlie cellular function and dysfunction.

Featured Projects

  • Adaptive Prediction of Yeast

    How Microbes Learn to Predict the Future

    Like plants and animals, even microbes can anticipate and prepare in advance for future changes in their environment
    Similar to how Pavlov trained a dog to anticipate food when it heard a bell, ISB researchers trained yeast to anticipate a lethal toxin when it sensed caffeine
    The study revealed how in a very short period of time yeast can evolve to ‘learn’ and ‘predict’ new patterns in their environment

  • Introduce One-cell Doubling Evaluation of Living Arrays of Yeast! ODELAY!

    Genes, Genomes, Genetics, scientists at Institute for Systems Biology introduce ODELAY, a powerful automated and scalable growth analysis platform that uses time-lapse microscopy to photograph individual yeast cells growing into colonies.

  • Predicting Cell Fate Decisions Using Single-Cell Analysis and the Theory of Tipping Points

    ISB researchers developed a new theory to exploit burgeoning single-cell molecular profiling measurements to make predictions of future cell behaviors.

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