Scanning EM of bacteria being eaten by white blood cell Photo Credit: Adrian Ozinsky 3 Bullets: Nearly a decade ago, ISB’s Baliga Lab published a landmark paper describing cMonkey, an innovative method to accurately map gene networks within any organism from microbes to humans. Two new papers describe the benchmark results of cMonkey and also the release of cMonkey2, which performs with higher accuracy. Using this approach, genetic and molecular…
Traditional node-link diagram of a network of yeast protein-protein and protein-DNA interactions with over 3,000 nodes and 6,800 links. Data from: von Mering et. al. Nature, 417, 399-403, May 2002; Lee et. al. Science, 298: 799-804 (2002) The node-link diagram above is a “hairball” of biological network data. Because it’s such a large network, it’s hard to scan for patterns or interesting interactions worth further investigation. But Bill Longabaugh, a…
