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Featured News

Drs. Wei Wei and Jim Heath

Posted: March 20, 2025

Cancer Press Release Heath Lab
Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It

Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It

ISB researchers have uncovered a stealth survival strategy that melanoma cells use to evade targeted therapy, offering a promising new approach to improving treatment outcomes.

Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It
Melanoma Starts Evading Treatment Within Hours – Here’s How to Stop It

Posted: February 18, 2025

Health Press Release Gibbons Lab
Scientists Decode Diet From Stool DNA – No Questions Asked

Scientists Decode Diet From Stool DNA – No Questions Asked

ISB’s Gibbons Lab developed a breakthrough method that analyzes food-derived DNA in fecal metagenomes, allowing for data-driven diet tracking without the need for burdensome questionnaires.

Scientists Decode Diet From Stool DNA – No Questions Asked
Scientists Decode Diet From Stool DNA – No Questions Asked

More News (Understanding Tumors)

 

Posted: May 19, 2025

Cancer Events Huang Lab
Beyond Faulty Genes: Sui Huang Presents a Cancer Paradigm Shift

Beyond Faulty Genes: Sui Huang Presents a Cancer Paradigm Shift

ISB Professor Sui Huang challenges the long-held belief that genetic mutations primarily drive cancer, offering a fresh perspective that could revolutionize how we think about and treat this complex disease.

Beyond Faulty Genes: Sui Huang Presents a Cancer Paradigm Shift
Beyond Faulty Genes: Sui Huang Presents a Cancer Paradigm Shift
Sui Huang's illustration of cancer attractors on the epigenetic landscape

Posted: March 26, 2025

Cancer Press Release Huang Lab
ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay

Sui Huang challenges the prevailing view of cancer as purely genetic in a new essay published in PLOS Biology. Huang and colleagues suggest non-genetic factors and disrupted gene regulatory networks may play crucial roles in cancer development.

ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay
ISB’s Sui Huang Challenges the Genetic Paradigm of Cancer in New Essay
screenshot of video for Heath PACT

Posted: March 8, 2023

Cancer Press Release Heath Lab
How Immune Cells ‘See’ and Respond to Mutations in Cancer Cells

How Immune Cells ‘See’ and Respond to Mutations in Cancer Cells

In a just-published paper in the journal Nature, a collaborative team of researchers from ISB, UCLA, PACT Pharma, and beyond analyzed T-cell responses in melanoma patients who were treated with different immune checkpoint inhibitors, and how those responses evolved over time.

How Immune Cells ‘See’ and Respond to Mutations in Cancer Cells
How Immune Cells ‘See’ and Respond to Mutations in Cancer Cells
Glioblastoma tumor slice and corresponding density map

Posted: June 29, 2021

Cancer Press Release Heath Lab
Looking at Tumors Through a New Lens: New Research May Improve Efficacy of Glioblastoma Immunotherapy

Looking at Tumors Through a New Lens: New Research May Improve Efficacy of Glioblastoma Immunotherapy

To improve the efficacy of neoadjuvant immune checkpoint blockade against glioblastoma, researchers are looking for vulnerabilities in surgically removed tissues – a difficulty due to the vast differences within the tumor and between patients. To address this, ISB researchers and their collaborators developed a new way to study tumors.

Looking at Tumors Through a New Lens: New Research May Improve Efficacy of Glioblastoma Immunotherapy
Looking at Tumors Through a New Lens: New Research May Improve Efficacy of Glioblastoma Immunotherapy
Dr. Wei Wei and Dr. Xiaowei Yan

Posted: March 9, 2021

Cancer Press Release Wei Lab
A Better Way to Find Circulating Tumor Cells in Non-Small Cell Lung Cancer Patients

A Better Way to Find Circulating Tumor Cells in Non-Small Cell Lung Cancer Patients

Despite the aggressive nature of Non-Small Cell Lung Cancer (NSCLC), circulating tumor cells that lead to metastases often go undetected in the blood. ISB researchers in Dr. Wei Wei’s lab and their collaborators have developed a novel method to better detect these circulating cells.

A Better Way to Find Circulating Tumor Cells in Non-Small Cell Lung Cancer Patients
A Better Way to Find Circulating Tumor Cells in Non-Small Cell Lung Cancer Patients
CRI iAtlas banner

Posted: December 18, 2020

Cancer Thorsson-Shmulevich Lab Understanding Tumors
CRI iAtlas Expands to Interactive Analysis of Data on Immunotherapy Treatments

CRI iAtlas Expands to Interactive Analysis of Data on Immunotherapy Treatments

CRI iAtlas is a comprehensive web-based resource that allows oncologists and researchers to study and analyze interactions between tumors and the immune microenvironment. The iAtlas team released immuno-oncology modules that allow investigators to access and work with genomics data from trials of treatment with immune-checkpoint inhibitors. 

CRI iAtlas Expands to Interactive Analysis of Data on Immunotherapy Treatments
CRI iAtlas Expands to Interactive Analysis of Data on Immunotherapy Treatments
View All News

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