The prize recognizes foundational discoveries about regulatory T cells and the FOXP3 gene that redefined immune tolerance and opened avenues to treat autoimmune disease, enable transplantation, and advance immuno-oncology. ISB celebrates Dr. Brunkow’s leadership and collaborative science.
The pioneering work of Mary Brunkow and Fred Ramsdell began with a mysterious mutant mouse known as “scurfy,” leading them to identify the FOXP3 gene and unlock how regulatory T cells prevent autoimmune disease — discoveries that now point to new treatments in cancer and autoimmunity.
ISB’s Dr. Alice Kane explores the biology of aging, highlighting frailty as a key measure of healthspan, new biomarkers of aging, and insights into menopause and women’s health.
ISB hosted the Systems Biology of Aging Virtual Workshop in May 2024 for graduate students, postdocs, principal investigators, industry scientists, and educators. The course provided practical tools for performing multi-omic systems biology analyses to advance the study of aging.
ISB is excited to announce the arrival of our newest faculty member, Ling/Obrzut Assistant Professor Dr. Alice Kane. The Kane Lab will investigate the biological determinants of frailty in both males and females. In this Q&A, she discusses her research to date, her areas of interest, and much more.