ISB News

The Other Malaria: Finding New Targets for a Vaccine Against Plasmodium vivax

Warhol style Plasmodium

A new report in PLOS Neglected Tropical Diseases describes the results of an international collaboration led by researchers at ISB and Seattle’s Center for Infectious Disease Research (CIDResearch). We used mass spectrometry-based proteomics to identify nearly 2,000 proteins present in Plasmodium vivax parasites, one of the Plasmodium species that cause the disease malaria in humans. The work was done on parasites dissected from mosquito salivary glands, parasites that were in the form that is transmitted from mosquitoes to humans. Because parasite proteins can potentially be recognized by the body’s immune system, the proteins we have identified are promising targets for new vaccines against malaria.

Read More

Recent Articles

  • Spotlight on ISB Education graphic

    2023-24 School Year ISB Education Highlights

    In the final installment of the 2023-24 academic year roundup, we highlight some of the top projects the ISB Education team is working on. Throughout the summer, the ISB Education was busy publishing research in a special edition of Connected Science Learning, hosting interns, and much more.

  • 2024 ISB Virtual Microbiome Series

    Our multi-day microbiome-themed virtual course and symposium is back for the fifth year! ISB is hosting a two-day course on October 16 & 17, 2024, followed by a symposium on October 18, 2024 titled, “A gut feeling: Microbes and their impacts on our minds.” Both events are virtual and free.

  • Fluidized bed reactor

    How Microbes Evolve to Spatially Divide and Conquer an Environment 

    ISB researchers examined representative organisms of two classes of microbes whose interaction contributes to the conversion of more than 1 gigaton of carbon into methane every year. They found that gene mutations selected over a relatively short timeframe in the two microbes led to distinct functions.