{"title":"ISB Researchers Identify New Protein Modification Critical to TB Pathogen Growth","description":"<p>ISB and Seattle BioMed researchers collaborated and discovered a new protein post-translational modification in the human pathogen Mycobacterium tuberculosis (Mtb). Post-translational modifications are essential mechanisms used by cells to diversify protein functions and ISB scientists identified the rare phosphorylated tyrosine post-translational modification on Mtb proteins using mass spectrometry. Inhibiting phosphotyrosine modified amino acids in Mtb severely limits the growth of this widespread deadly pathogen.<\/p>","url":"https:\/\/www.systemsbiology.org\/research\/new-protein-modification-critical-to-growth-of-tuberculosis-pathogen-found\/"}