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New research highlights strengths of large language models in uncovering social determinants of health while underscoring the need for human oversight and improved de-identification methods.
While at Washington University in St. Louis, Venkatesh and colleagues identified a novel gut microbial enzyme that impacts satiety-related signaling pathways in undernourished children treated with microbiota-directed complementary foods.
There has been an explosion of research into the two-way communication between the gut microbiota and the brain. This year, ISB hosted a virtual microbiome series dedicated to exploring the gut-brain axis.
Everybody poops, but not every day. An ISB-led research team examined the clinical, lifestyle, and multi-omic data of more than 1,400 healthy adults. How often people poop, they found, can have a large influence on one’s physiology and health.
Netflix’s “Hack Your Health: The Secrets of Your Gut” is a documentary that merged gut microbiome experts, four individuals – including a well-known hot dog eating champion – facing personal battles with gastrointestinal health, and a unique, effective visual method of “showing” the gut microbiome in action.
ISB researchers have developed a novel way to simulate personalized, microbiome-mediated responses to diet. They use a microbial community-scale metabolic modeling (MCMM) approach to predict individual-specific short-chain fatty acid production rates in response to different dietary, prebiotic, and probiotic inputs.