{"title":"Architecture of a Macromolecular Complex Regulating Gene Expression and DNA Repair Determined","description":"<p>ISB researchers and collaborators map the architecture of the TFIIH complex using powerful crosslinking-mass spectrometry (CXMS) technology and integrative modeling. Structural maps provide critical insights into how mutations in TFIIH subunits lead to disease phenotypes.<\/p>","url":"https:\/\/www.systemsbiology.org\/research\/researchers-determine-architecture-of-a-macromolecular-complex-regulating-gene-expression-and-dna-repair\/"}